This Project Grant from the National Institutes of Health's National Institute on Aging, under the Aging Research program (CFDA 93.866), provides $4,638,424 to the University of California, San Diego from August 1, 2022 to July 31, 2025. The grant will support research developing novel quantitative magnetic resonance imaging techniques to directly image myelin and quantify myelin content and properties in the brain. Specifically, the researchers will use ultra-short echo time sequences with echo times less than 1 millisecond to detect signal from myelin and map its T1 and T2 values. Developing non-invasive imaging methods to accurately evaluate myelin could provide critical insights into the pathogenesis and diagnosis of Alzheimer's disease, as well as monitoring treatment effectiveness, given myelin's indispensable role in cognitive functions.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $2.3m | 7/18/22 | ||
| Not listed | $2.3m | 7/18/22 |