Project Grant R61NS149204
- The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, awarded The Ohio State University $180,240 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into the mechanisms by which the neuronal TRPM2 ion channel affects post-stroke cognitive impairment. The project uses genetic animal models and adeno-associated viruses to conditionally knockout...
- The National Institute of Neurological Disorders and Stroke, a division of the Department of Health and Human Services National Institutes of Health, awarded The Ohio State University $586,866 on May 6, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and validate a cellular transplantation therapy for cervical spinal cord injury using human induced pluripotent stem cell-derived deep cortical neurons. The recipient will...
- The National Institute of Neurological Disorders and Stroke awarded a cooperative agreement to Case Western Reserve University for $1,202,540 on September 1, 2026, to conduct an exploratory trial of the RESTORES (Revolutionary Electrical Stimulation Technology to Optimize Recovery of Everyone with Spinal Cord Injury) system. The recipient will customize and program open-source Networked Neuroprosthesis (NNP) components—a modular peripheral neurostimulation device designed to address multiple...
- The National Institute of Neurological Disorders and Stroke awarded The Ohio State University $433,125 on May 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and optimize a three-dimensional total internal reflection fluorescence structured illumination microscope (3D TIRF-SIM) for investigating synaptic vesicle exo-endocytosis coupling in living cells. The research addresses a critical gap in neuroscience by...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The Ohio State University $300,154 on November 27, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating how pediatric traumatic brain injury (PTBI) and early life stress interact to impair prefrontal cortex development and cognition, with a focus...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded The Ohio State University $424,333 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop a bioengineered blood-brain barrier-on-a-chip microphysiological system for improved drug screening in primary brain tumors. The project addresses the challenge of modeling glioblastoma cellular...
- The National Science Foundation awarded Impulse Wellness LLC $304,997 on July 1, 2026, under the SBIR Fast-Track program to design and validate a wearable electromyography-based stroke rehabilitation system. The recipient will develop a sensor-embedded textile garment integrating reusable electrodes tailored to specific muscles and therapeutic activities, connected to built-in sensors to track muscle electrical activity during dynamic exercises and deliver real-time biofeedback. The system...
- The National Institute of Neurological Disorders and Stroke awarded The Cleveland VA Medical Research & Education Foundation $572,132 on August 22, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to design and test a prototype noninvasive electrical stimulation device and determine its effect on bladder control for women with spinal cord injury–related neurogenic bladder dysfunction. The project targets bladder hyperreflexia,...
- The National Institute of Neurological Disorders and Stroke awarded the University of Texas at Austin $393,284 on June 13, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct basic research on synaptic structural plasticity and stroke rehabilitation. The project examines how the brain remodels neural circuitry following stroke, with focus on reactive synaptogenesis—the growth of new connections among surviving neurons near...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $433,125 to the University of Texas Health Science Center at San Antonio on August 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of REST (Restrictive Element-1 Silencing Transcription Factor) in governing post-stroke neural plasticity and recovery. The...
The National Institute of Neurological Disorders and Stroke awarded The Ohio State University $791,792 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and adapt a wearable electromyography-triggered functional electronic stimulation (EMG-FES) system for stroke rehabilitation. The funded work focuses on engineering the NeuroLife Sleeve, a research-grade prototype sleeve embedded with 150 dual sensor/FES electrodes that simultaneously record muscle activation intent via surface electromyography and deliver closed-loop electrical stimulation to facilitate upper-limb motor recovery in stroke survivors. The system aims to bridge a critical clinical gap: more than 80% of stroke patients fail to regain complete function in affected arms despite conventional physical rehabilitation. The team will adapt the prototype for clinical deployment by occupational therapists, moving from research use to independent clinical application. The Ohio State University is the prime recipient. The research team includes collaborators from Battelle Memorial Research Institute and the University of Texas at Dallas, though the source does not specify sub-award amounts or pass-through arrangements. Performance occurs in Columbus, Ohio. The period of performance runs from September 1, 2026, through August 31, 2027. The assistance type is a Project Grant, classified as basic research support within NINDS's extramural research portfolio.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $791.8k | 8/24/26 |