Project Grant R61HL175860
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $639,165 project grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The Washington University to develop an equitable and accessible wearable device for continuous calculation of blood loss for postpartum hemorrhage (PPH). PPH is the leading cause of maternal mortality worldwide, with disturbing racial disparities in the U.S. The research aims to create a non-invasive, light-based sensor system that can...
- This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the federal Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $2,328,157 to develop a miniaturized, disposable CMOS-based point-of-care (POC) system for detecting biomarkers in complex samples. The key innovations include aptamer switches that generate binding-specific electrochemical signals without sample preparation,...
- The National Institutes of Health (NIH) awarded a $387,078 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to The Washington University in Missouri. This award, with a performance period from August 1, 2025 to April 30, 2029, aims to develop a wearable, AI-integrated, multimodal uterine monitoring system. The system will combine electrical and mechanical signal analysis to offer a more comprehensive understanding of uterine activity during pregnancy and labor, with the...
- The University of Pittsburgh was awarded a $300,000 federal Project Grant from the National Heart Lung and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837) to conduct research on "REAL-TIME EVALUATION OF ACUTE MYOCARDIAL INFARCTION WITH MULTI-LEAD ECG MONITORING FROM WEARABLE PPG MEASUREMENTS". The grant, awarded on September 15, 2025, will support the university's research efforts to advance the scientific understanding of cardiovascular health through the...
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $237,827 to Brigham & Women's Hospital Inc. to develop a wearable, non-invasive optical device for continuous blood pressure monitoring in neonates. The device, called CNAP-FlexNIRS, will use near-infrared spectroscopy and photoplethysmography to collect high-resolution pulsatile waveforms and...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $349,734 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Actiox LLC, a biomedical technology company in Thousand Oaks, California. The project aims to develop a wearable microneedle-based biosensor for continuous, real-time cardiac troponin I monitoring. The goal is to demonstrate the feasibility of this transformative biosensor technology to enable earlier detection of ischemic events and...
- This $200,000 Project Grant awarded by the National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems under CFDA 47.041 (Engineering) aims to develop and implement a novel testing platform to evaluate the accuracy of wearable photoplethysmography-based blood pressure monitoring devices. The University of Maryland, College Park will construct a bench flow phantom that simulates physiologically relevant blood pressure, blood flow, anatomical, and optical...
- The National Heart, Lung, and Blood Institute (NHLBI), through the Cardiovascular Diseases Research grant program (CFDA 93.837), awarded a $549,125 project grant to Rutgers, The State University of New Jersey to conduct a hybrid type II effectiveness-implementation randomized controlled trial (RCT) evaluating the Mobile-based Obstetric Monitoring for Hypertension and/or Diabetes (MOM-HD) program. The project aims to assess the effectiveness and implementation of the MOM-HD program, which...
- This Project Grant award of $371,021 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of a continuous respiratory monitoring platform to better classify apnea of prematurity (AOP) in premature newborns. The primary products to be delivered are: 1) a multimodal system and machine learning model to accurately detect and classify the major types of AOP (central, obstructive, and mixed); and 2) an optimized prototype system...
- This $2,623,234 federal Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) supports the development of a wearable multiplex biosensor system to monitor exacerbation risk in patients with chronic obstructive pulmonary disease (COPD). The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center is the prime awardee, collaborating with researchers at the California Institute of Technology...
The University of California, Irvine was awarded a $392,500 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) to develop the Maternal Obstetric Monitoring System (MOMS), a wearable device for early detection of postpartum hemorrhage (PPH). The project aims to design and validate an alpha prototype sensor that integrates a MEMS-based blood pressure sensor and a continuous signal integration (CSI) sensor, as well as determine design requirements for a beta prototype. The goal is to create a robust wearable system that can continuously monitor physiological waveforms to provide a more accurate and timely indication of PPH compared to current commercially available technologies. The project period is from Sep 1, 2025 to Jul 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $392.5k | 8/26/25 |