This federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the CFDA 93.279 Drug Use and Addiction Research Programs provides $2,214,862 to Duke University to conduct a study titled "NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings." The award aims to optimize and test the efficacy of a co-packaged long-acting injectable pre-exposure prophylaxis (LAI PrEP) and extended-release buprenorphine (XR-B) intervention for people in carceral and community re-entry settings in Maryland and Washington, D.C. Key sub-awardees include the University of Arkansas for Medical Sciences, Friends Research Institute, and The Miriam Hospital, who will contribute research coordination, data analysis, and clinical expertise to the project. The study's objectives are to develop the intervention protocol, evaluate implementation facilitation strategies, and compare the effectiveness of the LAI PrEP + XR-B intervention to oral PrEP + sublingual buprenorphine.
Generated 3/4/25, 6:56 AM