Project Grant R61AI187074
Award Date 9/10/25
Completion Date 8/31/28
Dollars Obligated $412K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $431,143 Project Grant to Tufts University School of Medicine under the Allergy and Infectious Diseases Research program (CFDA 93.855). The purpose of this 3-year grant, beginning January 23, 2025, is to develop methods for continuous in vitro propagation of the parasite Babesia microti, which is responsible for increasing rates of human babesiosis in the Northeastern U.S. Specifically, the grant will fund research to...
- This $616,588 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to understand the molecular function of unstudied genes in the fungal pathogen Cryptococcus neoformans, a leading cause of fungal meningitis. The research team at the University of California, San Francisco constructed and phenotypically profiled a comprehensive gene deletion collection for C. neoformans to elucidate the...
- This $346,582 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support the development of novel statistical and computational methods for genetic epidemiology. The key products and services to be delivered under this 5-year award include: Efficient coalescent-based phylodynamic methods to jointly infer genealogies and model parameters from pathogen genetic data, incorporating...
- This federal Project Grant award of $828,820 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to Weill Medical College of Cornell University aims to investigate the molecular mechanisms by which the commensal bacterium Enterococcus faecalis transitions from a harmless gut resident to a pathogen that can breach the intestinal barrier and cause life-threatening systemic infections. The key objectives are to: 1) Define how E....
- This Project Grant award of $782,178 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to develop new antifungal agents against sterolglycoside enzymes found in fungal pathogens. The research team at Stony Brook University is using a high-throughput screening approach to identify inhibitors of the sterolglycoside enzymes SGL1 and SGLA, which are essential for the pathogenicity of Cryptococcus neoformans and Aspergillus...
- This $412,581 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research to define the roles of specialized mitochondrial DNA polymerases (POLIB and POLID) in the replication and maintenance of the complex kinetoplast DNA network of African trypanosomes. These parasites cause neglected tropical diseases such as human African trypanosomiasis, Chagas disease,...
- The federal Project Grant award of $7,037,583 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to understand the mechanisms of nuclear egress in herpesviruses. The grant funds a collaborative research project led by Tufts University School of Medicine to expand structural and functional studies of the nuclear egress complex (NEC) across different herpesvirus families, visualize the...
- This Project Grant award of $3,178,626 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to investigate the interactions between the enteric pathogen Yersinia pseudotuberculosis and microfold (M) cells in the gastrointestinal epithelium. The award to Tufts University School of Medicine, with a performance period from Aug 2025 to Jul 2029, will utilize a differentiated human ileum organoid model to study how...
- This Project Grant awarded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $431,004 to the University of California, Davis to investigate the dynamic interplay between human cells and the pathogenic amoeba Entamoeba histolytica during the process of "trogocytosis" or cell-nibbling. The research aims to further understand the mechanisms by which E. histolytica attacks and kills human cells, with the goal of...
- This federal Project Grant award for $571,071.00, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand and develop protective measures against enterotoxigenic E. coli (ETEC) infections in infants. ETEC is a leading cause of diarrhea that is associated with significant morbidity, mortality, and stunting in children. The award will fund research at The Johns Hopkins...