Project Grant R56NS146174
- The National Institute of Neurological Disorders and Stroke awarded Emory University $575,485 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of the BCL11A gene in neuron function and neurological disease. The award funds research examining how BCL11A, a zinc-finger transcription factor, contributes to intellectual disability, autism spectrum disorder, epilepsy, schizophrenia, and...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $149,190 on July 26, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct functional and biochemical analysis of RNA exosome variants linked to neurological disorders. The award funds research analyzing missense mutations in the EXOSC5 subunit of the RNA exosome complex to understand how each mutation alters RNA exosome function and leads...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $577,611 on January 23, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate how cell-specific neural activity contributes to resting-state functional magnetic resonance imaging (rs-fMRI) patterns in the brain. The research develops and deploys simultaneous wide-field optical imaging (WOI) and rs-fMRI methodology to detect...
- The National Institute of Mental Health awarded Emory University $780,866 on July 2, 2026, under the Mental Health Research Grants program (CFDA 93.242) to support research on human induced pluripotent stem cell (hiPSC) and progenitor heterogeneity as predictors of variability in three-dimensional human neural differentiation. The award funds the Brain Organoid Hub at Emory University to investigate why region-specific brain organoids derived from hiPSCs exhibit high variability in...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $234,750 on May 11, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate NMDA receptor regulation of rapid synaptic scaling and spinal excitability in fragile X syndrome. The research will identify mechanisms controlling maturation of network excitability during neonatal development, with focus on how NMDA receptor blockade triggers...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $428,218 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop subcellularly resolved spatial genomics approaches for studying axon regeneration. The research maps the nerve regenerative landscape by building a three-dimensional spatial single-cell transcriptomics atlas of dorsal root ganglia in mice, training a...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $174,296 on December 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to study the dynamics of chromosomal instability in glioblastoma within the neural microenvironment. The recipient will investigate chromosomal instability (CIN) and extrachromosomal DNA (ecDNA) formation in glioblastoma tumors using human-induced pluripotent stem...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $460,839 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to cultivate rigor in movement neuroscience research by aligning professional incentives with rigorous study design practices. Emory will establish community-focused programs to address the reproducibility crisis in movement neuroscience by creating incentives that...
- Federal Grant Award Summary Emory University received a $430,375 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective July 1, 2025 through June 30, 2027. The award funds research to elucidate the mechanisms of altered RNA transport dynamics caused by KIF1C (Kinesin-3 motor protein) mutations in heterospastic paraplegia type 58 (SPG58), a...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $618,523 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on September 1, 2026, for research on scalable, affordable artificial intelligence-driven clinical decision support for movement disorders. The project addresses misdiagnosis and access barriers in Parkinson's disease care, particularly the underdiagnosis of psychiatric symptoms and limited...
The National Institute of Neurological Disorders and Stroke awarded Emory University $547,750 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate human-specific mechanisms governing miR-124 regulation of neuronal development. The research focuses on microRNA biogenesis and function in the human brain, specifically examining how miR-124—the most abundant microRNA in brain tissue—controls spatiotemporal development and function of human neurons. The project addresses the gap between rodent-based miRNA research and human-specific biological pathways, with particular emphasis on how miR-124-3p and miR-124-5p strands regulate the human neuronal proteome and control neuronal lineage development from neural progenitor cells onward. The work encompasses mechanisms underlying miR-124 dysregulation across neurodevelopmental, neuropsychiatric, and neurodegenerative disorders, with findings intended to support development of miR-124-based therapeutics for brain disorders. Performance occurs in Atlanta, Georgia. The award carries a period of performance from September 1, 2026, through August 31, 2027. Emory University, a tax-exempt non-profit research institution headquartered in Atlanta, receives the award through its Office of Sponsored Programs Division.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $547.8k | 8/27/26 |