Project Grant R01NS146515
- The National Institute of Neurological Disorders and Stroke awarded Emory University $635,512 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and validate an automated deep brain stimulation programming platform for patients with Parkinson's disease. The project will develop machine learning algorithms and a closed-loop automated system to optimize deep brain stimulation parameters—including contact...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $460,839 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to cultivate rigor in movement neuroscience research by aligning professional incentives with rigorous study design practices. Emory will establish community-focused programs to address the reproducibility crisis in movement neuroscience by creating incentives that...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $927,014 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to validate a diagnostic lipid biomarker panel for idiopathic Parkinson's disease. The R61 phase of this project will develop a quantitative liquid chromatography-mass spectrometry assay for eight lipid biomarkers discovered in red blood cells that distinguish idiopathic...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $540,901 on April 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate molecular mechanisms underlying dopamine signaling dysfunction in advanced Parkinson's disease. The research examines how striatal projection neurons become maladaptive during disease progression and why L-DOPA therapy loses efficacy over time. The work focuses...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $577,611 on January 23, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate how cell-specific neural activity contributes to resting-state functional magnetic resonance imaging (rs-fMRI) patterns in the brain. The research develops and deploys simultaneous wide-field optical imaging (WOI) and rs-fMRI methodology to detect...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $430,375 on June 22, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop x-ray dark-field imaging technology for carotid hemodynamic analysis using anisotropic iron oxide nanorods as contrast agents. The research addresses cerebrovascular disease assessment and plaque vulnerability prediction by advancing grating-based interferometric...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $234,750 on January 26, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate neuromodulation of somato-sympathetic postganglionic activity after spinal cord injury. The research develops animal models incorporating clinically analogous epidural spinal cord stimulation to understand how neuromodulation can restore autonomic function...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $547,750 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate human-specific mechanisms governing miR-124 regulation of neuronal development. The research focuses on microRNA biogenesis and function in the human brain, specifically examining how miR-124—the most abundant microRNA in brain tissue—controls spatiotemporal...
- The National Institute of Mental Health awarded Emory University $780,866 on July 2, 2026, under the Mental Health Research Grants program (CFDA 93.242) to support research on human induced pluripotent stem cell (hiPSC) and progenitor heterogeneity as predictors of variability in three-dimensional human neural differentiation. The award funds the Brain Organoid Hub at Emory University to investigate why region-specific brain organoids derived from hiPSCs exhibit high variability in...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $428,218 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop subcellularly resolved spatial genomics approaches for studying axon regeneration. The research maps the nerve regenerative landscape by building a three-dimensional spatial single-cell transcriptomics atlas of dorsal root ganglia in mice, training a...
The National Institute of Neurological Disorders and Stroke awarded Emory University $618,523 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) on September 1, 2026, for research on scalable, affordable artificial intelligence-driven clinical decision support for movement disorders. The project addresses misdiagnosis and access barriers in Parkinson's disease care, particularly the underdiagnosis of psychiatric symptoms and limited specialist availability in rural areas. The research will develop AI tools to enhance neurologists' workflows and support personalized treatment prediction while addressing clinical adoption challenges including algorithmic bias, interpretability, and validation in real-world settings. The work incorporates existing clinical infrastructure at the recipient site, which records three-dimensional kinematics, multi-view video, and inertial measurement units alongside standardized motor assessments as part of routine clinical care, and will extend to telehealth platforms to quantify mental health impacts. Performance occurs in Atlanta, Georgia, with a completion date of August 31, 2031. The award is classified as a Project Grant. Emory University's Office of Sponsored Programs is the recipient organization.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $618.5k | 8/17/26 |