Project Grant R56MH137986
- Federal Grant Award Summary The National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), awarded UCLA a project grant of $125,556 (obligated October 25, 2025) to investigate the neuronal correlates of avoidance and pursuit during human ambulatory navigation. This three-year research initiative, scheduled for completion by November 30, 2028, will examine how the medial temporal lobe—including the hippocampus, amygdala, nucleus accumbens, and...
- Federal Grant Award Summary The University of Massachusetts Medical School received a $612,425 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on March 15, 2026, with a completion date of December 31, 2030. This longitudinal research project investigates visual discrimination and anxiety in children, with the primary objective of identifying trait-based neural markers associated with anxiety disorder risk...
- This federal Project Grant award of $444,125, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research investigating the role of the serotonergic system in social behavior following early life adversity. The research team at George Washington University will utilize electrophysiology, behavioral assays, and fiber photometry to examine how early life stress alters the excitability of serotonergic neurons and...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Texas Health Science Center at Houston $780,000 under the Mental Health Research Grants program (CFDA 93.242) on April 15, 2025, to support research investigating hypothalamic prodynorphin neurocircuits and their role in integrating defensive behaviors. The project, titled "Hypothalamic Prodynorphin Neurocircuits Integrating Defensive Behaviors," will run through February 28, 2030,...
- Federal Project Grant Award Summary The University of California, San Diego received a $415,664 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on March 15, 2026, with a completion date of December 31, 2030. This award supports a research project investigating the dissociable roles of distinct orbitostriatal circuits in value-based decision-making. The research employs advanced neuroscientific...
- Federal Grant Award Summary The National Institute of Mental Health awarded a $1.46 million Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Massachusetts General Hospital effective September 15, 2025, through September 14, 2027. The award supports research on "Effect of Network-Based Real Time Neurofeedback Augmentation of Mindfulness Practice on Recurrent Negative Thinking in Adolescents at Risk for Serious Mental Illness." MGH will develop and...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $150,104 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective December 30, 2025, with completion targeted for June 30, 2028. The grant supports basic neuroscience research investigating intracellular signaling mechanisms that dynamically control synaptic responses in the basal ganglia, specifically focusing on the...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded Trustees of Boston University a $449,625 Project Grant under the Mental Health Research Grants program (CFDA 93.242) beginning March 15, 2026, and concluding March 14, 2028. This research initiative investigates the molecular, cellular, and circuit-level mechanisms underlying working memory maintenance—a critical cognitive function severely impacted by neuropsychiatric diseases. The project employs advanced...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Miami a Project Grant totaling $731,258 on March 1, 2026, under the Mental Health Research Grants program (CFDA 93.242). The award supports a longitudinal neuroimaging research study investigating the neural dynamics underlying internalizing disorders, specifically Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD). The research leverages high-stakes, real-world...
- This project grant, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports fundamental neuroscience research investigating cell type-specific mechanisms of glutamatergic synapse function and organization. Awarded to Tufts University School of Medicine on October 17, 2025, with $136,050 obligated through October 23, 2027, the research focuses on understanding how impaired inhibitory signaling contributes to...
This federal Project Grant award of $606,029.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research at the University of Massachusetts Medical School (UMass Medical) to investigate the neurocircuitry underlying motivated reward-seeking behavior in response to stress. The key goals of the research are to: 1) Determine if a subpopulation of GABAergic neurons in the medial habenulo-interpeduncular (MHB-IPN) axis is activated by acute stress and exhibits reduced activity during reward behaviors, contributing to stress-induced increases in motivation for sucrose seeking; 2) Test if a subpopulation of IPN neurons projecting to the laterodorsal tegmental area mediates reward seeking during stress through modulation of dopaminergic reward circuits; and 3) Examine how acute stress engages IPN afferents critical for the effects of stressors on reward behavior and seeking. This research aims to elucidate the circuitry and mechanisms underlying stress-coping behaviors and the impacts of stress on reward-related processes, which may provide insights into dysregulated behaviors in neuropsychiatric disorders and inform potential therapeutic strategies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $606.0k | 7/23/24 |