Project Grant R21MH140102
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded Trustees of Boston University a $147,486 Project Grant under the Mental Health Research Grants program (CFDA 93.242) effective September 28, 2025, with completion anticipated April 30, 2028. This research initiative, titled "Pathways to Loneliness in First-Episode Psychosis: Testing the Sociodevelopmental Model," delivers a mixed-methods investigation examining the relationships between loneliness,...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Virginia a $768,909 Project Grant under the Mental Health Research Grants program (CFDA 93.242) effective May 1, 2025, through January 31, 2030. This research initiative, titled "Synchronous Network Activity in the Maturing Prefrontal Cortex: Mechanistic Impact of Birth Timing and Serotonin," investigates how premature birth affects brain development and cognitive function. The...
- Federal Grant Award Summary The Scripps Research Institute received a $878,601 Project Grant award from the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), effective April 1, 2026, with completion targeted for December 31, 2030. This collaborative research program delivers advanced neuroscience research services focused on understanding how neural circuits in the mammalian brain reorganize to encode new memories. The project combines...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a $804,690 Project Grant under the Mental Health Research Grants program (CFDA 93.242), effective June 12, 2025 through April 30, 2030. This research project investigates the relationship between N-acetyl-aspartyl-glutamate (NAAG), a peptide neurotransmitter, and memory deficits in schizophrenia patients in mid- to late-life. The primary deliverable involves measuring NAAG levels using...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the Regents of the University of Michigan a $3.97 million Project Grant (CFDA 93.242 - Mental Health Research Grants) effective August 1, 2025, through July 31, 2028, to develop a scalable high-plex pipeline for whole-brain proteomics profiling. The project addresses a critical gap in neuroscience research by creating a comprehensive proteomics atlas of the mammalian brain, complementing existing transcriptomics...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Miami a Project Grant totaling $731,258 on March 1, 2026, under the Mental Health Research Grants program (CFDA 93.242). The award supports a longitudinal neuroimaging research study investigating the neural dynamics underlying internalizing disorders, specifically Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD). The research leverages high-stakes, real-world...
- Federal Grant Award Summary Boston University Medical Campus received a $191,972 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on September 8, 2025, with a completion date of August 31, 2030. The award supports a pilot randomized controlled trial examining an adapted form of Cognitive Processing Therapy (CPT) for posttraumatic stress disorder (PTSD) in populations experiencing health disparities. The...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Broad Institute of MIT and Harvard a $475,388 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to conduct basic neuroscience research investigating the transcriptional and neuro-immune consequences of KDM5B loss in bipolar disorder (BD). The award, initiated June 16, 2025, and extending through June 15, 2027, supports a two-year research initiative examining how genetic...
- Federal Grant Award Summary Massachusetts Institute of Technology (MIT) received a $1,378,301 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on May 1, 2025, with a completion date of February 28, 2030. The research project investigates neuron-glial interactions in basal ganglia circuitry, specifically examining the role of striatal astrocytes in modulating dopamine signals and facilitating behavioral...
- Federal Grant Award Summary Florida State University's Sponsored Research Administration Division received a $301,998 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded April 1, 2026, with completion scheduled for January 31, 2031. The award funds research investigating the effects of memory reactivation on episodic recall and brain function, specifically examining how concurrent and differential reactivation...
The National Institute of Mental Health (NIMH) awarded Trustees of Boston University a $449,625 Project Grant under the Mental Health Research Grants program (CFDA 93.242) beginning March 15, 2026, and concluding March 14, 2028. This research initiative investigates the molecular, cellular, and circuit-level mechanisms underlying working memory maintenance—a critical cognitive function severely impacted by neuropsychiatric diseases. The project employs advanced neuroscientific methodologies including multi-area two-photon calcium imaging, long-range anatomical tracing, cell-resolution optogenetic manipulation, and spatial transcriptomic analysis to map working memory circuits across multiple biological scales. The research deliverables include comprehensive empirical findings distinguishing working memory maintenance from sensory-to-working-memory transformations and identification of cellular and molecular mechanisms supporting local working memory function. By systematically investigating how stimuli are maintained in working memory through monitoring and perturbation of cortical activity patterns, this research advances fundamental understanding of neural mechanisms relevant to preventing and treating cognitive impairments associated with mental health and neuropsychiatric conditions. The award supports Boston University's established research infrastructure and neuroscience expertise in conducting federally funded mental health research initiatives.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $449.6k | 3/5/26 |