This federal Project Grant award from the National Human Genome Research Institute (NHGRI), under the Human Genome Research program (CFDA 93.172), supports research to develop models for predicting the impact of genetic variants on mRNA stability, translation, and protein levels. The University of Washington will receive $1,273,296 to conduct high-throughput reporter assays characterizing how variants in coding and non-coding regions affect mRNA and protein measures, and to develop machine learning approaches that integrate these results to generate predictive models. The grant, awarded on September 25, 2024, will fund this work through the ultimate completion date of August 31, 2025. This research aims to improve the interpretation of genetic variants and their association with disease phenotypes, a critical challenge in genomics.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $0 | 1/16/25 | ||
| Not listed | $636.6k | 9/25/24 | ||
| Not listed | $636.6k | 9/25/24 |