Project Grant R56ES037652
- The National Institute of Environmental Health Sciences awarded $114,072 to Rutgers The State University of New Jersey, School of Nursing, on September 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate mechanisms of micro-nanoplastics uptake, translocation, and toxicity in in vitro human intestinal models. The research explores how micro-nanoplastics—small plastic particles from environmental breakdown of waste—enter and cross biological barriers, particularly the...
- The National Institute of Environmental Health Sciences awarded New York University $10.907 million on September 15, 2025, under the Environmental Health program (CFDA 93.113) to conduct a translational study on the accumulation of micro- and nanoplastic particles in mammalian tissues. The research investigates inter-tissue accumulation of micro- and nanoplastic particles across the lifespan, including the quantified concentration of these particles within systemic tissues, the role of sex, age,...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $167,928 under the Environmental Health Project Grant program (CFDA 93.113) on April 1, 2026. The project investigates lipoprotein-mediated nanoplastic uptake and transport across the placenta. The research addresses how micro and nanoplastics translocate into placental tissue and the role chylomicrons may play in facilitating this process. The working hypothesis posits that...
- The National Institute of Environmental Health Sciences awarded $117,938 to Rutgers The State University of New Jersey, School of Nursing on January 1, 2026, under the Environmental Health program (CFDA 93.113) to fund Project Grant F31ES037190. The recipient will examine prenatal cadmium exposure, placental transporter proteins, and child health outcomes. The work leverages existing data from an estimated 4,763 mother-child pairs across 13 cohorts in the NIH's Environmental Influences on...
- The National Institute of Environmental Health Sciences awarded Baylor College of Medicine $639,797 on April 1, 2026, under the Environmental Health program (CFDA 93.113) to characterize the association between micro- and nanoplastic particle (MNP) exposure and preterm birth and to map the inflammatory and immunological mechanisms by which placental exposure to MNP drives adverse pregnancy outcomes. The research quantifies temporal patterns of MNP accumulation across 3,500 biospecimens (maternal...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $429,504 to New York University (NYU) School of Medicine to characterize human exposure to microplastics during pregnancy. The overarching aim is to leverage existing infrastructure from the NYU Children's Environmental Health Study (NYU CHES) to measure and characterize microplastics in placental tissue collected from the general...
- The National Institute of Environmental Health Sciences awarded $760,000 to the University of California, San Diego on August 26, 2026, under the Environmental Health program (CFDA 93.113) for a Project Grant to develop a placenta-brain axis-on-a-chip platform for studying prenatal neurotoxicity. The recipient will construct a physiologically integrated human co-culture system coupling placental trophoblasts, maternal immune cells, fetal endothelial cells, and cortical organoids via...
- The National Institute of Environmental Health Sciences awarded $765,348 to the University of California, Davis on April 14, 2026, under the Environmental Health program (CFDA 93.113) to investigate pollutant-adsorbed nanoplastics and their health impacts following inhalation exposure. The research addresses the formation, distribution, and neurotoxic effects of composite particles created when airborne pollutants adsorb onto nanoplastics. The study employs advanced label-free imaging...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $152,500 on August 15, 2026, under the Environmental Health program (CFDA 93.113) to define dose-response relationships and renal functional impairment from simultaneous exposure to micro- and nano-plastics and arsenic. The research establishes a quantitative framework for how micro- and nano-plastics behave when co-present with arsenic in the body, whether their excretion is...
- The National Institute of Environmental Health Sciences awarded the Board of Regents of the University of Nebraska $1,479,178 on September 9, 2025, under the Environmental Health program (CFDA 93.113) to quantify the release of nano- and microplastics from plastic food containers into water and beverages and assess potential health risks. The project measures the release of nano- and microplastics from reusable plastic cups, single-use water and soft drink bottles, and takeaway coffee cups...
The National Institute of Environmental Health Sciences awarded New Jersey Institute of Technology $759,977 for a Project Grant (R56ES037652) on September 1, 2026, under the Environmental Health program (CFDA 93.113). The award funds investigation of placental translocation and toxicity of environmentally relevant nanoplastics—plastic particles smaller than one micron that accumulate in human organs and may disrupt health during sensitive developmental windows. NJIT will study placental toxicity using in vivo rodent models and in vitro human placental organoid models, with particular focus on how particle characteristics such as shape and weathering state affect uptake, accumulation, and toxicity. The research directly compares environmentally relevant nanoplastics with pristine polystyrene spheres to guide future research methodology. The first aim investigates nanoplastic distribution in mouse placenta following prenatal exposure; the second aim compares toxicity across nanoplastics of varying physicochemical properties, specifically examining links between disrupted tissue architecture and estrogen signaling. The award period runs through August 31, 2027, with place of performance in New Jersey.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $760.0k | 8/20/26 |