The National Institute on Deafness and Other Communication Disorders (NIDCD), a division of the National Institutes of Health (NIH), awarded a $828,022 Project Grant under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program to James Madison University. The grant will support research to identify, for the first time in humans, nonlinearity in cervical and ocular vestibular evoked myogenic potentials (VEMPs) - responses that reflect activation of the otolith...
This federal Project Grant award of $2,025,057 from the National Institute on Deafness and Other Communication Disorders (CFDA 93.173 - Research Related to Deafness and Communication Disorders) will fund research at the University of Washington aimed at understanding the molecular mechanisms by which vestibular hair cells (HCs) develop and maintain their specialized structures critical for sensory transduction and synaptic transmission. The objective is to generate new knowledge that can...
This Project Grant award of $265,410 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program, supports research to better understand the role of mechanoelectrical transduction (MET) components in vestibular hair cell maturation and gene therapy responsiveness. The research aims to characterize how the heterogeneous regional expression of MET subunits contributes to differences in...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $589,483 to Wayne State University to assess in vivo changes in central neuronal activation, molecular indicators of synaptic transmission, and motor function in response to vestibular nerve hypofunction generated by noise exposure. The project aims to evaluate the contributions of...
This federal Project Grant award, with ID R21DC022412, was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program. The grant will fund research to study how peripheral vestibular signals, generated by hair cells in the inner ear, create vestibular compound action potentials (VCAPs) that are used in the coordination of gaze, orientation, and motor movement. The goal is to...
The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $274,440 Project Grant under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program to The Ohio State University. The project, titled "Investigating the Impacts of Vestibular and Auditory Function on Spatiotemporal Gait Characteristics and Spatial Navigation," aims to elucidate the interplay between age-related auditory and vestibular deficits and their effects on gait and...
This $659,164 Project Grant awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to identify pharmacological modulators, endogenous ligands, and binding partners for the orphan G protein-coupled receptor GPR156. The grant, awarded to the University of Rochester, will leverage innovative cell-based assays and proximity-mediated labeling technologies to discover new...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support research to investigate the mechanisms underlying the olivocochlear system's ability to enhance cochlear function in mice. The $416,642 award, valid from July 2024 to June 2026, will enable researchers at the University of Rochester to: 1) isolate and systematically evaluate the...
This Project Grant award of $169,292 from the National Institute on Deafness and Other Communication Disorders (CFDA 93.173 - Research Related to Deafness and Communication Disorders) supports research to investigate the heterogeneity and molecular regulation of vestibular ganglion neurons (VGNs) and their synaptic terminals on hair cells in the vestibular system. The project aims to: 1) Classify VGNs by their transcriptional profiles and correlate this to their anatomical subtypes, and 2)...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), will provide $693,856.00 to The Regents of the University of California, San Francisco (UCSF) to conduct research on the structure and function of coordinated neural activity in the auditory system of mice. The 5-year project aims to use high-channel-count electrophysiology, optogenetics,...