This $659,164 Project Grant awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to identify pharmacological modulators, endogenous ligands, and binding partners for the orphan G protein-coupled receptor GPR156. The grant, awarded to the University of Rochester, will leverage innovative cell-based assays and proximity-mediated labeling technologies to discover new compounds that can modulate the activity of GPR156, which is a clinically relevant target for the treatment of hearing and balance disorders. The ultimate goal is to better understand the biology of this understudied orphan receptor and develop novel therapeutic approaches for addressing related communication disorders.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $659.2k | 8/15/24 |