Project Grant R44HL142391

This $205,735 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports the development of an antimicrobial blue light-activatable optical endotracheal tube (Optical-ETT) to combat biofilms on endotracheal tubes and prevent ventilator-associated pneumonia. The research project aims to conduct in vitro studies to evaluate the anti-biofilm efficacy of the Optical-ETT, as well as...

This Project Grant, awarded by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), aims to develop a unique antimicrobial vascular catheter to prevent catheter-related bloodstream infections (CRBSI). The $272,702 award, effective September 1, 2023, with a completion date of February 29, 2024, will support research and development efforts to create an intravascular catheter with inherent long-lasting antiseptic properties. The...

Acatechol, Inc. was awarded a $274,982 National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I grant to develop an innovative anti-infective coating for Foley catheters. The project aims to create a hybrid coating that combines biofilm-repellent and antimicrobial properties to provide prolonged resistance against pathogen colonization and catheter-associated urinary tract infections (CAUTIs). This work is being conducted under the NSF Technology, Innovation, and...

The Cooperative Agreement award, funded by the Uniformed Services University of the Health Sciences under the Uniformed Services University Medical Research Projects program (CFDA 12.750), is for the development of "SELF-DEPLOYING, INSTRUMENTED, SHAPE-MEMORY POLYMER ENDOTRACHEAL TUBES FOR NON- EXPERT, AUTONOMOUS EMERGENCY INTUBATION AND MONITORING OF THORACIC INJURIES IN BATTLEFIELD CONDITIONS". The $2,862,000.00 award, with a performance period from December 15, 2023 to December 14,...

This $256,000 National Science Foundation project grant supports the development of an automated chest tube to prevent clotting. Circulatech LLC will design and prototype a novel chest tube that proactively manages fluid flow within the catheter lumen to flush and drain the tube, reducing blood clot formation. Through a process called "dilutional coagulopathy," the tube will use sterile saline or anticoagulants to reduce thrombosis in the drainage space rather than relying on...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant awarded $274,440 to Vine Medical Inc., a for-profit manufacturing company, to develop a proof-of-concept for a self-deploying endotracheal intubation device. The proposed soft robotics system aims to achieve over a 90% first-pass intubation success rate, which would improve patient outcomes and reduce complications during emergency airway management procedures. The device is designed to...

This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop a catheter end cap with an antimicrobial luminal insert to reduce the risk of bloodstream infections in hemodialysis patients. The $591,844 award to Allvivo Vascular, Inc. will fund the development and characterization of a prototype "Gatekeeper Antimicrobial Barrier...

The National Science Foundation awarded a $256,000 Small Business Technology Transfer Phase I Project Grant to develop a minimally invasive articulating intubation stylet. The grant period runs from June 15, 2021 through May 31, 2022 under the Engineering (47.041) program. This program aims to foster innovation and excellence in engineering research and education across various fields. Funds will support the awardee, located in Blaine, Minnesota, to research and develop a new medical device...

This federal Project Grant award, with an ID of R43HL172530, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The $295,203 award supports the development of a novel polymer additive product called HaloAdd by Halomine Inc., a Cornell University-affiliated small business. The goal is to create an antimicrobial and antifouling polymer additive that can be blended into thermoplastic polyurethane (TPU) materials to...

The National Institute on Aging awarded Theranova LLC, a veteran-owned medical device company, a $1,438,762 Project Grant (CFDA 93.866 - Aging Research) to develop the Entarik system, a low-cost enteral feeding tube system that provides real-time confirmation of feeding tube location during insertion and monitors for unintentional dislodgement. The project aims to verify the system's ability to detect shallow airway insertion, design a second-generation feeding tube with reduced manufacturing...