This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $295,561 to Biosensing Instrument Inc. to develop a commercial prototype of a multi-functional Plasmonic Scattering Microscopy (PSM) instrument. The PSM technology enables high-throughput, label-free quantification of membrane protein binding kinetics on single cells in their native microenvironment. This addresses an unmet...
This $349,566 Project Grant award from the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports the development of Biosensing Instrument Inc.'s Spotting-Free Nano-Oscillator Array (SFNOA) technology.
The SFNOA system aims to provide high-throughput, label-free quantification of ligand binding kinetics to transmembrane proteins in their native states. Key innovations include the use...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development and commercialization of the Acoustodrop technology. The Acoustodrop is an acoustic-based, programmable, contactless liquid-handling system that can manipulate and dispense droplets in a high-throughput, biocompatible manner. Key features of the Acoustodrop platform include high throughput (>2,500...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is developing a microfluidic device for rapid and inexpensive pathogen detection in rodent animal health surveillance. The goal is to create a device that can be used cage-side to complement existing quarterly room/rack monitoring, enabling faster outbreak mitigation and health status confirmation for animal importation. The key...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program provides $349,816 to Narwhal Bio, Inc. to develop a prototype instrument, software, and consumable for non-invasive, live-cell identification, tagging, and downstream characterization. The goal is to enable researchers to study clinically relevant cell-cell interactions, which drive many challenging diseases like cancer, autoimmunity, and...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provided $947,705 to Applied Biophysics, Inc. to develop an innovative "Cell Assurance Monitor" (CAM) instrument. The CAM is designed to assist researchers in detecting issues such as cell line misidentification, mycoplasma contamination, and changes in cell populations during long-term cell culture. By monitoring the...
This Project Grant award, totaling $298,999.00, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The funding supports the development of a novel imaging platform for high-throughput, high-content analysis of extracellular vesicles (EVs) at the nanoscale level. The goal is to create an innovative technology that can rapidly detect and characterize diverse EV subpopulations, including exosomes...
The National Science Foundation (NSF) awarded a $568,480 Project Grant under the Engineering (CFDA 47.041) program to The Regents of the University of Colorado, doing business as the University of Colorado, to conduct research on a novel biosensing concept for high-sensitivity measurement of cell mechanical biomarkers. The 3-year award, effective May 1, 2024, will investigate how biological cells with different mechanical properties interact with acoustic waves propagating along a substrate,...
This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to develop next-generation acoustic reporter genes for biomedical applications. The $375,371 award, which began on September 10, 2024 and runs through July 31, 2029, is being led by William Marsh Rice University. The research aims to address limitations in the assembly and performance of gas...
This $228,697 National Science Foundation award under the Engineering program (CFDA 47.041) will support the development of an optical biosensor technology to facilitate drug screening and validation efforts. Auctus Biologics, Inc. will utilize a proprietary temperature, pH, and chemically stable protein composed of two fragments that bind with antibody-like affinity and specificity. Over the one-year period ending January 2023, the company will establish the technology's suitability for...