Project Grant R44DK145399
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Delphi Stem, Inc. $306,863 on August 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop a framework for evaluating type 2 diabetes medication efficacy using patient-derived cellular models. The recipient will generate personalized islet-like aggregates from patient cells to predict drug responsiveness and tailor treatment regimens, with the goal of improving...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Daecos LLC $619,274 on August 6, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and validate an artificial intelligence-driven clinical decision support system for predicting acute dialysis needs in critically ill patients. Daecos will refine its proprietary algorithms using retrospective data from three UC San Diego hospitals, deploy the system within UC...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Utah $321,828 on September 16, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop predictive models for personalized type 2 diabetes pharmacotherapy. The project, titled "DREAM: Building Equitable Predictive Models for Personalized Diabetes Pharmacotherapy," will develop a set of predictive models leveraging cross-institutional...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded President and Fellows of Harvard College $698,321 on September 1, 2026, to develop agentic and generative artificial intelligence systems for in silico modeling of human pancreatic tissue in Type 1 Diabetes under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). Harvard will develop two integrated computational platforms: FUSEMAP, extending a deep learning framework to integrate...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Yale University $755,834 under Project Grant R01DK149276 on August 15, 2026, to evaluate an integrated multimodal digital health platform for type 2 diabetes management. The award funds a three-arm randomized controlled trial enrolling 300 adults with type 2 diabetes to assess a unified digital health intervention that synchronizes continuous glucose monitoring data, wearable device outputs (sleep and physical...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Healthpartners Institute $314,000 on July 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and test RISE-CGM (Real-Time Insights for Smart Engagement with CGM), a digital behavior change intervention targeting type 2 diabetes self-management. RISE-CGM is a 28-week scalable intervention (16 weeks active, 12 weeks maintenance) that delivers evidence-based...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $5.136 million to the University of Washington on September 25, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop artificial intelligence-designed mini-proteins (epibinders) that enhance the differentiation of pluripotent stem cells into functional pancreatic islets for cell replacement therapies in diabetes. The project addresses variable efficiency in current...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Illinois $160,575 on July 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Project Grant K01DK147658). The award funds a three-year study of Medicaid alternative payment model (APM) implementation and evidence-based practice adoption in federally qualified health centers (FQHCs) to improve diabetes outcomes. The research addresses how FQHCs, which...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Scripps Health $331,277 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to fund research integrating continuous glucose monitoring (CGM) in diabetes self-management education and support to improve glycemic control in Latino adults with type 2 diabetes. The research, titled "Integrating Continuous Glucose Monitoring in Diabetes Self-Management...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Johns Hopkins University $1.638 million on September 11, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct research using continuous glucose monitoring systems and machine learning methods to identify glucose pattern clusters and high-risk subgroups in persons with and without diabetes. The project, titled "Glucose Patterns and Clinical Outcomes in the...
The National Institute of Diabetes and Digestive and Kidney Diseases awarded Updoc AI $1.467 million on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and evaluate the UPDOC Clinical Copilot, an AI agent that directly manages medication prescriptions to improve glycemic control in type 2 diabetes mellitus. The project, titled Titration Response and Enhancement by AI Tools for T2DM (TREAT-T2DM), focuses on optimizing outcomes for underserved populations disproportionately affected by type 2 diabetes. The Clinical Copilot will be assessed for effectiveness in achieving glycemic control (HbA1c), with the broad objective of validating the technology as a scalable solution to address barriers including inadequate access to primary care, low treatment adherence, and delayed therapeutic intensification that currently hamper disease management in underserved groups. Work is performed in Los Altos, California, with a period of performance from September 1, 2026, through February 29, 2028. The funding is structured as a Project Grant, the assistance type for extramural research supporting improved prevention, diagnosis, and treatment of diabetes and related diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 8/19/26 |