Project Grant R44DK141401
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $687,416 Project Grant under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) to Lynntech Inc., a small business technology development company based in College Station, Texas. The grant will support the development of a cutaneous gel to deliver a therapeutic with an intriguing mechanism of action to effectively treat diabetic foot ulcers (DFUs). The project aims to: (1) prepare,...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $555,034 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Emory University. The project, titled "Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation (CARE-D-FOOT-NAV), A Randomized Controlled Trial", aims to assess the impact of a comprehensive patient navigator program on improving diabetic foot ulcer (DFU) care...
- This federal Project Grant award of $1,187,347.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) will support research conducted by the University of California, San Diego (UC San Diego) to develop photoacoustic imaging tools to monitor and predict the response to treatment for diabetic foot ulcers (DFUs). The research aims to validate imaging biomarkers that can measure tissue perfusion and...
- The federal Project Grant award of $310,438 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program) to Htic, Inc. (UEI: XAMZMYUY9UA9) is focused on establishing proof-of-concept studies to develop a novel humanized monoclonal antibody (hCITH3-mAb) for the treatment of diabetic wounds. The project aims to formulate a topical delivery system for hCITH3-mAb and conduct in vivo studies to demonstrate...
- This Project Grant award of $806,274 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) supports the development of "Wearable Insoles for Recurrent Diabetic Ulcer Prevention (WIREDUP)". The goal is to evaluate the effectiveness of an interactive sensory insole device in reducing the recurrence of diabetic foot ulcers (DFUs) in adults with diabetes. The project will be conducted by The Johns Hopkins University, a leading federal research grantee, and...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $268,377 to The University of North Texas Health Science Center at Fort Worth (UNTHSC) to develop and evaluate a novel device for accelerating the healing of diabetic foot ulcers (DFUs) using high-frequency, low-amplitude vibration (HFLAV). The key objectives are to: 1) enhance...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a component of the National Institutes of Health, awarded a $350,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Microvascular Tissues, Inc. The grant supports the evaluation of a microvascular tissue graft treatment in rat models of diabetic peripheral neuropathy. The project aims to assess the ability of this novel microvascular tissue graft to improve...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $389,019 Project Grant to Koronis Biomedical Technologies Corp. (KBT) to evaluate the feasibility of using an innovative smart offloading ankle foot orthosis (AFO) to treat patients with diabetic foot ulcers, Charcot neuroarthropathy, and other below-the-knee orthopedic traumas. The proposed smart AFO allows...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is focused on developing novel bioengineered regenerative medicine solutions based on vasculogenic regenerative medicine technology. The $543,826 award, granted on December 10, 2024, aims to investigate the mechanisms underlying in vivo vasculogenic reprogramming, specifically examining...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $199,999 to the University of Florida to develop innovative artificial intelligence (AI)-based methods to support the discovery of potent, orally available small-molecule heparanase inhibitors. The goal is to evaluate these novel heparanase inhibitors in murine models as a...
This federal Project Grant award of $1,024,812 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop novel treatments for diabetic foot ulcers (DFU). The award supports research conducted by Epoulosis Therapeutics Inc. to leverage single-cell RNA sequencing data and in vivo studies to repurpose the drug metrifonate for enhancing wound healing in DFU patients. The project will culminate in the development of a wound bandage containing metrifonate-releasing biomaterials, with the goal of providing a more effective treatment option for this major complication of diabetes. The award has an ultimate completion date of July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 8/1/25 |