Project Grant R01DK141065
- This federal Project Grant award of $1,024,812 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop novel treatments for diabetic foot ulcers (DFU). The award supports research conducted by Epoulosis Therapeutics Inc. to leverage single-cell RNA sequencing data and in vivo studies to repurpose the drug metrifonate for enhancing wound healing in DFU...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $555,034 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Emory University. The project, titled "Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation (CARE-D-FOOT-NAV), A Randomized Controlled Trial", aims to assess the impact of a comprehensive patient navigator program on improving diabetic foot ulcer (DFU) care...
- This Project Grant award of $806,274 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) supports the development of "Wearable Insoles for Recurrent Diabetic Ulcer Prevention (WIREDUP)". The goal is to evaluate the effectiveness of an interactive sensory insole device in reducing the recurrence of diabetic foot ulcers (DFUs) in adults with diabetes. The project will be conducted by The Johns Hopkins University, a leading federal research grantee, and...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $268,377 to The University of North Texas Health Science Center at Fort Worth (UNTHSC) to develop and evaluate a novel device for accelerating the healing of diabetic foot ulcers (DFUs) using high-frequency, low-amplitude vibration (HFLAV). The key objectives are to: 1) enhance...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $687,416 Project Grant under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) to Lynntech Inc., a small business technology development company based in College Station, Texas. The grant will support the development of a cutaneous gel to deliver a therapeutic with an intriguing mechanism of action to effectively treat diabetic foot ulcers (DFUs). The project aims to: (1) prepare,...
- This $2,971,227 federal Project Grant, awarded on September 4, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to investigate the role of fatty acids in regulating cellular metabolism and protein synthesis in the context of fasting, inflammation, and metabolic diseases. The research aims to uncover novel signaling pathways through which fatty...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), funded under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop a noninvasive method for earlier detection of skeletal muscle insulin resistance and dysfunction as a precursor to type 2 diabetes. The $389,621 award will support prospective ultrasound imaging of skeletal muscles, concurrent laboratory testing, and analysis of muscle...
- This $2,833,514 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, titled "Renal Metabolism in AKI", will fund research to investigate changes in kidney metabolism in sepsis-associated acute kidney injury (AKI) and their impact on kidney tubule injury and recovery. The University of California, San Diego (UCSD) is the awardee...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is focused on developing novel bioengineered regenerative medicine solutions based on vasculogenic regenerative medicine technology. The $543,826 award, granted on December 10, 2024, aims to investigate the mechanisms underlying in vivo vasculogenic reprogramming, specifically examining...
- This $532,177 Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847), supports research to investigate a novel inflammatory pathway in diabetic kidney disease (DKD). The research aims to elucidate the role of the transcription modulator I-MFA in regulating inflammatory cytokine production by glomerular mesangial cells, a key contributor to DKD pathogenesis. The 4-year project at the University of North Texas Health Science Center will...
This federal Project Grant award of $1,187,347.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) will support research conducted by the University of California, San Diego (UC San Diego) to develop photoacoustic imaging tools to monitor and predict the response to treatment for diabetic foot ulcers (DFUs). The research aims to validate imaging biomarkers that can measure tissue perfusion and hypoxia in 3D to better understand DFU progression and identify at-risk tissue before ulcer relapse. This project builds on the university's prior pilot work demonstrating the potential of photoacoustic imaging to predict DFU therapy response with a high degree of accuracy. The award period runs from September 1, 2025 to August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 8/31/25 |