Project Grant R44DK122918

This Project Grant award of $306,873 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) aims to develop an AI-driven automated system for accurately generating Banff lesion scores from kidney biopsy slides. The project, titled "BANFF-AID: BANFF Automated Nephrology Feature Framework - Artificial Intelligence Diagnosis", will create custom AI models to extract...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), provides $249,000 to Case Western Reserve University to develop an ultrafast photoacoustic histology platform for real-time intraoperative diagnosis. The project aims to create a structured illumination ultraviolet photoacoustic microscopy system capable of...

This $1,470,094 project grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) will fund research by New York University School of Medicine to optimize pre-implantation kidney transplant biopsy interpretation using artificial intelligence (AI) assistance. The key products and services to be delivered under this 5-year project include: Developing a comprehensive unbiased atlas of histopathology in pre-implantation deceased donor kidney biopsies using...

This federal Project Grant award of $765,546, awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to develop a novel non-invasive method for assessing bone turnover in patients with chronic kidney disease (CKD). The project aims to evaluate a "virtual bone biopsy" approach using time-lapse high-resolution peripheral quantitative computed...

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $702,754 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Mayo Clinic to develop artificial intelligence-based methods for characterizing kidney macrostructure from pre- and post-nephrectomy computed tomography (CT) images. The goal is to evaluate automated imaging biomarkers as prognostic tools for predicting progressive chronic kidney disease in patients...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is providing $1,337,953.41 to the University of Arizona to develop and disseminate an advanced 2-photon Bessel beam light sheet (2PBLS) microscopy instrument for high-speed, sub-micron resolution volumetric imaging in deep tissue. The proposed instrument will enable faster...

This $152,453 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support the development and validation of a deep learning approach to automatically assess kidney vascular pathology and predict cardiovascular risk from digitized kidney biopsy images. The award will be used by the Boston Medical Center Corporation to: 1) develop and validate an...

The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded The Johns Hopkins University a $395,566 Project Grant under the Engineering (47.041) federal grant program. The grant funds research to develop new optical and computational tools to improve histological imaging of unprocessed tissues without the need for tissue slides. Specifically, the grantee aims to create a novel macroscope projecting ultraviolet illumination at high spatial...

The National Institutes of Health (NIH) awarded a $749,854 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to Albany Medical College to acquire an Olympus FVMPE-RS multiphoton microscope for intravital microscopy research. This specialized microscope will enable NIH-supported investigators at Albany Medical College and other nearby research institutions to conduct detailed mechanistic studies using mouse models of disease, covering a range of research areas including...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $358,062 to the University of Pittsburgh to conduct research on understanding kidney endothelial maturity and mesenchymal transition in vascularized human kidney organoids. The key objectives are to: 1) Determine if kidney organoid co-culture enables the induction of kidney-specific...