This Project Grant award of $306,873 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) aims to develop an AI-driven automated system for accurately generating Banff lesion scores from kidney biopsy slides. The project, titled "BANFF-AID: BANFF Automated Nephrology Feature Framework - Artificial Intelligence Diagnosis", will create custom AI models to extract...
This Project Grant award, ID R01DK138067, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $1,470,094 award supports the development of an artificial intelligence-powered tool to improve preimplantation kidney transplant biopsy interpretation and reduce inappropriate discard of potentially viable kidneys. Key objectives include constructing a comprehensive...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $351,377 to Mayo Clinic to develop artificial intelligence-based methods to characterize kidney macrostructure from pre- and post-nephrectomy computed tomography (CT) images. The overarching goal is to evaluate automated imaging biomarkers as prognostic tools for predicting...
This $166,643 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports the development of robust phenotyping pipelines for early detection of collagen type IV-associated nephropathy (COL4A-AN) using electronic health records (EHR) data. The primary goal is to establish scalable phenotyping methods that leverage natural language processing (NLP) and...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $725,420 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to develop an optimized allysine-targeted positron emission tomography (PET) probe and validate it in animal models and human renal biopsy samples. The goal is to establish a non-invasive...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $133,500 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Boston Medical Center Corporation (BMC) with a start date of September 1, 2024 and end date of August 31, 2026. The grant will fund research on the relationship between APOL1 genotypes and biomarkers of immune activation and tubular injury in the context of chronic kidney disease (CKD) in sub-Saharan...
The U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $243,750 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Trustees of the University of Pennsylvania. The grant will fund the development of novel methods to improve detection of mosaic chromosomal alterations (MCA) in non-neoplastic tissues like the kidney and blood. The project aims to create single-cell sequencing techniques and spatial...
This Project Grant award of $209,832, awarded on January 15, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research), will support a 5-year research project led by the New York University School of Medicine. The primary goals are to: 1) Deeply phenotype autonomic dysfunction in chronic kidney disease (CKD) using comprehensive testing, 2) Quantify the association between inflammation and autonomic...
This Project Grant award, valued at $128,286, was issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The goal of the project is to uncover the underlying cellular mechanisms that contribute to the effects of free fatty acid-induced lipotoxicity in kidney tubular epithelial cells and the development of chronic kidney disease (CKD). The research will be conducted at The...
This federal Project Grant award of $344,632 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research to evaluate the impact of recent changes to the kidney allocation system in the United States. The research aims to: (1) assess whether the supply of organs is equitably distributed among U.S. transplant centers under the new 250-nautical-mile kidney...