Project Grant R44AR064613

This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is developing the X-Visual, a sensor to track fracture healing in cannulated screws used for hip fracture fixation. The $299,999 award to Aravis Biotech LLC will cover the design, computational modeling, and initial testing of this innovative device that can non-invasively measure screw bending...

This Project Grant award from the National Science Foundation (NSF) Division of Materials Research, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $322,382 to the University of Connecticut Health Center (UCHC) from September 1, 2023 through August 31, 2026. The goals of this collaborative research project are to use computer modeling and high-energy synchrotron X-ray diffraction experiments to better understand how the incorporation of cobalt (Co) and chromium...

This $672,394.58 project grant from the National Institutes of Health's National Institute of Dental and Craniofacial Research Oral Diseases and Disorders Research program (CFDA 93.121) supports the development of a crosslinkable tissue particle implant for regenerating craniofacial bone. Led by Leefa Biotech LLC, the one-year award aims to demonstrate improved bone regeneration in critical-size cranial bone defects using the implant compared to the current standard of care. If successful, the...

This $252,906 National Science Foundation project grant supports the development of scalable manufacturing methods for peptide amphiphile molecules by Amphix Bio Inc. The goal is to advance a safer and more affordable alternative to recombinant proteins currently used in spinal fusion surgeries. Over 500,000 such surgeries are performed annually in the U.S. to treat back and neck pain. While peptide amphiphiles show promise for reducing biological dose needs and offering consistent outcomes,...

This Project Grant award from the National Science Foundation (NSF), under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, supports the development and validation of a novel, projection-based surgical navigation platform by Illuminant Surgical Inc. The $274,865 award, effective January 15, 2024, aims to create a system that projects visual anatomical references and guidance directly onto a patient's skin during minimally invasive spinal procedures. This is expected to...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award to Reselute, Inc. provides $998,921 to develop a novel implantable orthopedic medical device and procedure to reduce recovery duration and infection risks associated with severe traumatic fractures of the long bones. The project aims to advance a 3D-printed, antibiotic-releasing intramedullary nail to improve upon current standard-of-care implants that are prone to...

The National Science Foundation awarded a $254,360 Project Grant to Quiver Dental, Inc. under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a diagnostic device to measure dental implant stability. The one-year award running from August 1, 2022 to July 31, 2023 aims to complete proof-of-concept demonstration of a reliable and accurate device using vibrational technology to quantify the degree of motion and stability between a dental implant and surrounding...

Cornell University received a $100,000 Project Grant from the National Science Foundation to develop a tissue-engineered intervertebral disc with a biodegradable cage. The goal of the one-year project under the NSF Technology, Innovation, and Partnership's CFDA 47.084 program is to advance the commercial potential of a tissue-engineered solution to treat intervertebral disc degeneration. Intervertebral disc degeneration is a leading cause of disability in the United States, costing $100B...

This Project Grant award, totaling $685,594 and awarded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop innovative surgical and engineering approaches to improve vascularization and survival of 3D printed or bioprinted bone grafts for craniomaxillofacial (CMF) reconstruction. The project will leverage a novel microsurgical technique called "vascular micropuncture" to augment...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), funded under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a multi-spectral Kerrison rongeur (surgical instrument) capable of detecting dura and nerve roots during spinal surgery. The $306,735 award to Briteseed, LLC, a small business, will fund the creation of a prototype device with an integrated optical...