Project Grant R43NS107093

The National Institute of Neurological Disorders and Stroke (NINDS), through the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded Versapeutics Inc. a $2,380,552 federal project grant on September 18, 2023 to conduct toxicology and efficacy studies of their novel antibody therapeutic Versamab-101 for treating spinal cord injury. Versapeutics, a for-profit biotechnology company, will utilize the funding to evaluate the safety profile and determine...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $437,250 to the University of California, San Diego (UCSD) to conduct in vivo screening of combination gene therapies for axonal regeneration after spinal cord injury. The project aims to efficiently identify new combinations of genetic targets that can enhance both the...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports development of a novel screening technology to identify FDA-approved drugs that can promote functional recovery in spinal cord injury (SCI). The $411,136 award to the Texas A&M University System Health Science Center will fund a 3-step screening platform using adult cortical...

This $1,006,322 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will fund research to develop a regeneration classifier that can predict the regenerative potential of diverse neuronal types after spinal cord injury. The research, conducted by the University of California, San Diego, will expand on the team's prior success in using patch-based...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research on promoting axon regeneration and functional recovery after spinal cord injury. The $391,250 award to the University of Louisville will fund a 5-year study with the following key objectives: 1) Evaluating controlled PTEN deletion to overcome barriers to...

This $458,154 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant supports research by Microcures Inc. to develop a nanoparticle-encapsulated small interfering RNA (siRNA) therapy targeting the Fidgetin-like 2 (FL2) protein. This novel therapy aims to promote tissue repair and functional recovery after spinal cord...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $595,245 to the University of Florida to conduct research on the use of normobaric oxygen therapy to treat spinal cord injury. The key objectives are to determine if normobaric oxygen therapy can mitigate inflammation, preserve breathing function, and provide...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding research to develop a polymer-based drug delivery system to promote spinal cord repair. The $184,837 award to The Ohio State University will support experiments to optimize conditions for fabricating drug-loaded microspheres, characterize their release profiles, and evaluate...

This federal Project Grant award, valued at $427,625.00 and awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to explore whether electrical stimulation can enhance the capacity of neural stem cell transplants to improve recovery from chronic spinal cord injury. The study will be conducted by the University of Washington and will examine...

Axonis Therapeutics, Inc. was awarded a $316,091 Project Grant from the Department of the Army Medical Command under the Military Medical Research and Development program. The grant will support Axonis Therapeutics' efforts to accelerate translation of a small-molecule enhancer to promote recovery and reduce neuropathic pain after spinal cord injury using a pig model. Through September 2025, Axonis Therapeutics will conduct research to investigate medical solutions for injuries sustained on...