Project Grant R43MH143427
- The National Institute of Mental Health awarded $1,415,720 to Deliberate Solutions Inc. on August 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to advance AI-CLINICAL OUTCOME ASSESSMENT (AI-COA) for Depression toward regulatory qualification and commercial readiness as a drug development tool. The project funds technical development and clinical validation of AI-COA, a multimodal artificial intelligence tool designed to provide objective, standardized assessment of...
- The National Institute of Mental Health awarded The Leland Stanford Junior University $192,192 on April 15, 2026, to develop an artificial intelligence foundation model for functional neuroimaging that predicts treatment response, stratifies patients, and identifies biotypes in major depressive disorder under CFDA 93.242 (Mental Health Research Grants). The award funds three specific aims. Aim 1 applies pooled functional MRI data from individuals with major depressive disorder to fine-tune a...
- The National Institutes of Health Office of the Director awarded Trustees of Dartmouth College $300,000 on September 1, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to develop and pilot test THERABOT+, an enhanced artificial intelligence chatbot for mental health support integrating real-time biofeedback and passive sensing data. THERABOT+ extends prior research on THERABOT, a generative AI chatbot that demonstrated significant symptom reduction in depression and anxiety...
- Federal Project Grant Award Summary The National Institute of Mental Health awarded Empathy Rocks Inc. a Project Grant of $447,132 under the Mental Health Research Grants program (CFDA 93.242) for the period September 1, 2025 through August 31, 2026. The awardee will develop an artificial intelligence tool designed to standardize the administration and scoring of Clinical Outcome Assessments (COAs) in mental health clinical trials. This Phase I Small Business Innovation Research (SBIR) project...
- The National Science Foundation Division of Computing and Communication Foundations awarded Case Western Reserve University $420,082 on October 1, 2026, under the Computer and Information Science and Engineering program (CFDA 47.070) to develop a real-time, closed-loop human-robot interaction framework that enables robots to recognize and respond to human emotional distress through speech, gestures, and gentle touch. The research develops interpretable computational models that infer emotional...
- The National Institute of Mental Health awarded Oregon Research Behavioral Intervention Strategies, Inc. (doing business as Influents Innovations) $314,362 under the Mental Health Research Grants program (CFDA 93.242) on September 1, 2026, to develop a digital evidence-based app for providers and teens addressing depression and subclinical depressive symptoms in youth. The project addresses the gap between the prevalence of depressive symptoms in adolescents and access to treatment. Cognitive...
- The National Institute of Mental Health awarded the University of California, San Diego $2.115 million on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and evaluate a mobile health system delivering just-in-time adaptive interventions based on dialectical behavior therapy principles for young adults with comorbid major depressive disorder, social anxiety disorder, generalized anxiety disorder, and related anxiety conditions. The UNDERSTAND project...
- The National Institute of Mental Health awarded Children's Hospital Los Angeles $769,500 on March 15, 2026, under the Mental Health Research Grants program (CFDA 93.242) to evaluate the feasibility, acceptability, and preliminary effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth (CBT-DAY) delivered by clinicians with limited autism training to verbally-fluent autistic youth with depression. The project develops and tests CBT-DAY, an autism-adapted intervention...
- The National Institute of Mental Health awarded Brown University $299,660 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and evaluate "Chat for Hope," an AI-powered mobile mental health application designed to screen for and address depression, anxiety, and posttraumatic stress symptoms among trauma-exposed adolescents in Ukraine. The project is a collaborative R21/R33 effort between Brown University and the National Academy of...
- The National Institute of Mental Health awarded the University of Southern California $1.105 million on August 7, 2026, under the Mental Health Research Grants program (CFDA 93.242) to establish a global framework for harmonized functional MRI analysis in psychiatry. The project will harmonize resting-state fMRI datasets across eight psychiatric and neurodevelopmental disorders—schizophrenia, bipolar disorder, post-traumatic stress disorder, major depression disorder, obsessive compulsive...
The National Institute of Mental Health awarded Dream Face Technologies LLC $314,362 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and evaluate robot-administered cognitive behavioral therapy for older adults with depression. Dream Face Technologies will conduct a Phase I Small Business Innovation Research study using the Ryan Companionbot, an AI-powered humanoid socially assistive robot, to assess and treat older adults aged 65 and older with major depressive disorder. The work employs natural language processing and deep machine learning to deliver robot-administered cognitive behavioral therapy, a novel form of CBT developed for this study. The recipient will recruit 20 participants through the Lane Center at the University of Colorado, Colorado Springs, and measure feasibility and acceptability using the PHQ-9, GDS-30, Kim Alliance Scale for participant engagement, and DeJong Gierveld Loneliness Scale. Performance takes place in Denver, Colorado through August 30, 2027. The award is structured as a project grant to a domestic small business, the assistance type used for Phase I SBIR applications within the Mental Health Research Grants program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $314.4k | 8/21/26 |