This Project Grant award of $591,032 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to Square2 Systems Inc. in Hanover, NH. The funding will support the development of the "COGITO" platform, a turnkey solution for rapidly developing, evaluating, deploying, and scaling digital therapeutics for the prevention, treatment, and management of substance use disorders and other behavioral health conditions. The...
This $1,309,500 Project Grant awarded by the National Institutes of Health (NIH) under the Trans-NIH Research Support (CFDA 93.310) program supports the development of a novel digital psychiatry diagnostic framework that utilizes crowdsourcing algorithms to improve the specificity of machine learning models in distinguishing between autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in adolescents. The key products and services to be delivered under this 3-year...
Lifespan Digital Health LLC was awarded a $255,409 Project Grant from the National Science Foundation under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop bio-behavioral technology and provide mental health services. Specifically, the company will use predictive algorithms, wearable technology, and peripheral autonomic biofeedback to provide timely data and enable mental health professionals to treat students. This innovative approach aims to address the...
This federal Project Grant award of $780,698 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), aims to optimize the integration of human and digital support in a meditation app for depression and anxiety. The key products and services to be delivered include: The proposed study will conduct a hybrid factorial and micro-randomized trial to evaluate the effects of introductory coaching, on-demand email-based coaching, and digital...
This Project Grant award from the National Institute of Mental Health (CFDA 93.242 Mental Health Research Grants) provides $830,409 to Brigham & Women's Hospital Inc. to develop novel software and computational techniques that integrate real-time navigated electric-field mapping and source-space electroencephalogram (EEG) analysis during transcranial magnetic stimulation (TMS) treatments. The goal is to improve the accuracy of targeting and dosimetry for individualized patients to enhance...
This Project Grant award of $517,546, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to optimize, benchmark, and validate a novel multimodal microelectrode array (MEA) probe that integrates fast-scan cyclic voltammetry (FSCV) for sub-second neuromodulator sensing with parallel electrical recording. The research team, led by investigators from Dartmouth College, aims to develop this integrated MEA platform...
This Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) federal grant program provides $380,375 to Ceretype Neuromedicine Inc. to design and develop an advanced functional MRI (fMRI) software platform as a medical device for use in clinical trials and therapeutic applications in neuropsychiatry. The key objectives are to: 1) Engineer an fMRI system that meets regulatory requirements for industry-backed clinical trials,...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is supporting the development and validation of an AI-enabled virtual assistant app called CLAIRITY. The app aims to automate the identification of individuals at risk of suicide, depression, and anxiety, and guide them to appropriate interventions. The $458,782 award will enable the awardee, Clarigent Corporation, to characterize the effects of using an...
This Project Grant award of $334,588 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is focused on harnessing collective intelligence to predict clinical outcomes for individuals at high risk of developing psychosis. The key objectives are to: 1) Evaluate the predictive accuracy of a group of psychiatrists using clinical data individually and as a collective intelligence group, and 2) Assess the predictive performance of a...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA Program 93.242 (Mental Health Research Grants) provides funding to Nurelm Inc. to develop and test the LEMURDX system. LEMURDX is a software platform that uses machine learning and wearable device sensors to objectively measure hyperactivity in children with ADHD. The $615,908 award over 3 years will be used to refine the LEMURDX product to enhance ease of use for clinical researchers, and to test the...
This Project Grant award from the National Institute of Mental Health (NIMH), under CFDA Program 93.242 Mental Health Research Grants, provides $612,784 to Square2 Systems Inc. to finalize and assess the feasibility, technical merit, and commercial potential of the COGITO digital therapeutics (DTx) platform. COGITO is an editable version of the LADDR DTx platform that aims to provide a turnkey solution for rapidly developing, evaluating, deploying, and scaling DTx to prevent, treat, or manage a wide range of health conditions, with a focus on mental health in this initial phase. The project will involve usability testing of COGITO with clinical researchers in the mental health field to accelerate the pace and impact of science-based digital therapeutics. The award period is from September 1, 2024 to February 28, 2025.