Project Grant R01MH139342
Award Date
12/13/24
Completion Date
10/31/29
Dollars Obligated
$518K
Federal Agency
National Institute of Mental Health
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Hanover, NH 03755, USA
Similar Awards
This Project Grant award of $1,038,154 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports the development of a dual-function microelectrode probe that can simultaneously measure neurochemical and electrophysiological activity in the nervous system. The principal investigator, Dr. Alexander Zestos, is partnering with Spike Neuro LLC to refine carbon deposition processes for Spike Neuro's silicon microelectrodes and explore...
The National Institute of Mental Health (NIMH) awarded a $659,217 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of Puerto Rico to develop a novel neuropeptide Y (NPY)-sensitive microelectrode for real-time monitoring of endogenous NPY release. The objective is to create a sub-25 mm microelectrode that can measure NPY with sub-second time resolution, enabling research to establish connections between NPY levels and neurological disorders. By...
Purdue University was awarded a $1,304,216 Project Grant by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to develop and test a new platform for high-density 3D electrophysiology and two-photon calcium imaging in freely moving animals. The goal is to enable simultaneous recording of millisecond electrical dynamics and spatial mapping of neural circuit activity during natural behaviors to better understand how the brain processes...
This $449,228 Project Grant, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), will fund the development of an integrated system for long-term electrophysiological profiling of human brain organoids. The key products to be delivered are:
A biological assay chamber that supports chronic electrophysiology while maintaining organoid health;
High-fidelity, 3D neural probes for chronic, extracellular recording and stimulation;...
The National Institute of Mental Health (NIMH) awarded a $242,310 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Johns Hopkins University. The award supports research on "Head Scanning Behavior and Reward Interactions in Potentiation of Place Fields" from September 2024 to March 2026. The project aims to use in vivo electrophysiology recordings in the hippocampus to examine how rewards evoke head scanning behavior and influence place field...
The National Institute of Mental Health (NIMH) awarded a $753,016 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the Lieber Institute for Brain Development to validate electrophysiological biomarkers associated with performance in a preclinical assay of sustained attention. The 5-year project, starting on July 10, 2024, aims to optimize a rodent continuous performance test (CPT) paradigm, evaluate the impact of amphetamine on electrophysiological correlates of behavior, and...
The National Institute of Mental Health (NIMH) awarded a $107,948 Project Grant to The Johns Hopkins University under the Mental Health Research Grants program (CFDA 93.242) to conduct research on single neuron computations within brain-wide circuits. The research project, titled "Studying Single Neuron Computations Within Brain-Wide Circuits," aims to leverage novel imaging technologies to measure the input and output signals of individual cortical neurons in vivo and model the...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will provide $2,565,783 to Oregon Health & Science University (OHSU) from September 1, 2023 to August 31, 2026 to develop novel genetically encoded sensors and actuators for monitoring and manipulating neuromodulatory signaling activities in the brain at the cellular and circuit levels. The project aims to enable large-scale in vivo...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, was awarded to Intelligent Imaging Innovations, Inc. (3i) to establish the feasibility of developing a commercial instrument for large-scale, all-optical electrophysiology. The $505,311 award, spanning January 1, 2025 to December 31, 2026, seeks to combine recent advancements in optical techniques, such as volumetric imaging of neural activity and...
This federal Project Grant award for $248,998 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The grant will fund research conducted by the Trustees of Dartmouth College to investigate the role of GABA/glutamate co-transmission in the ventral tegmental area (VTA) of the brain and its impact on motivation-related behaviors relevant to mental health disorders like major depression and bipolar disorder.
The research...