Project Grant R43MH135524
- This Cooperative Agreement, awarded by the National Institute of Neurological Disorders and Stroke (part of the National Institutes of Health), supports a $4,451,386 project to adapt and implement a Nurse Care Management model to provide comprehensive chronic pain management for rural patients. The project, funded under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to adapt an evidence-based Nurse Care Management approach that includes care coordination, cognitive behavioral...
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is intended to develop and evaluate an adaptive psychological intervention to improve pain management and reduce opioid use following an injury. The $264,995 grant, awarded on September 15, 2025, will fund the optimization and feasibility testing of a two-part intervention. The first part is a 15-minute computerized brief intervention focused on...
- The U.S. National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,643,228 Cooperative Agreement grant under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to Worcester Polytechnic Institute (WPI) to develop an Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment (IMPACT). The key objectives of this 2-year IMPACT project are to: 1) Initiate a clinical trial of Mindfulness-Based Stress Reduction (MBSR) for chronic low back pain...
- This federal Project Grant award, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop a guided, web-based intervention combining Acceptance and Commitment Therapy (ACT) for chronic pain and Mindfulness-Based Relapse Prevention (MBRP) for substance use disorders. The $188,307 award, effective September 1, 2025 through August 31, 2029, will support the principal investigator Dr. Edwards and her mentorship team at...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded a $431,643 Project Grant to The Research Foundation for the State University of New York (RF SUNY) to develop and test a telehealth-delivered, pain-targeted motivational smoking cessation intervention for smokers with chronic pain who are not ready to quit. The project aims to overcome barriers to in-person treatment by delivering the intervention via telehealth in a Stage 1...
- The University of Washington was awarded a $1,024,374 Cooperative Agreement by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a large, multi-site pragmatic 3-arm cluster randomized control trial. The project, titled "Equitable Primary Care for Pain Care (EQUIP PC)", aims to adapt an Integrated Behavioral Health in Primary Care (IBH-PC) toolkit to improve equitable access to chronic pain...
- This $817,330 Project Grant awarded by the National Center for Complementary and Integrative Health (CFDA 93.213 - Research and Training in Complementary and Integrative Health) supports research to develop an adaptive intervention that improves pain outcomes for patients with chronic low back pain (CLBP) and insomnia who do not respond to cognitive behavioral therapy for insomnia (CBTI) alone. The study will enroll 300 patients with comorbid CLBP and insomnia in CBTI, and then investigate if...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $399,870 to 2Morrow Inc. to accelerate the commercialization and dissemination of their evidence-based digital behavioral therapeutic for individuals with chronic pain. The funding will be used to hire a fractional Chief Commercial Officer (CCO) to review and validate 2Morrow's commercialization plan, and then execute a...
- This Project Grant award of $4,649,740 from the National Institute of Neurological Disorders and Stroke (part of the National Institutes of Health) under the Drug Use and Addiction Research Programs (CFDA 93.279) is funding research to develop network-based models for understanding inter-individual differences in the progression of chronic musculoskeletal pain, using knee osteoarthritis as a case study. The research aims to: 1) Use natural language processing to annotate patient narratives and...
- This Project Grant award of $409,612 from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) will support research investigating the neurobiological mechanisms underlying self-regulation and pain catastrophizing in chronic pain patients, with a focus on fibromyalgia. The primary research objectives are to: (1) evaluate the effect of cognitive-behavioral therapy (CBT) on neural mechanisms of catastrophizing self-regulation, assessed using real-time fMRI...
TRAINING PSYCHOLOGISTS AND NURSE PRACTITIONERS IN THE USE OF AN EVIDENCE-BASED ONLINE PAIN SELF-MANAGEMENT PROGRAM: LEVERAGING THE POWER OF EXPERT GUIDANCE AND TELEHEALTH - SUMMARY/ABSTRACT OVER 100 MILLION ADULTS IN THE U.S. LIVE WITH CHRONIC PAIN. THEY FACE RISKS SUCH AS PROLONGED OPIOID USE, DEPRESSION, ANXIETY, STRESS, AND VARIOUS SOCIAL, OCCUPATIONAL, AND FINANCIAL PROBLEMS. EVEN THOUGH OPIOIDS WERE TRADITIONALLY USED TO MANAGE CHRONIC PAIN, THEY ARE NO LONGER THE PRIMARY OPTION DUE TO THEIR NUMEROUS RISKS (E.G. OVERDOSE, ADDICTION). THE CDC AND OTHER AUTHORITIES CURRENTLY ADVOCATE THE USE OF NON-OPIOID INTERVENTIONS FOR PAIN MANAGEMENT. ALTHOUGH THE SHIFT IN POLICY HAS SUCCESSFULLY DECREASED OPIOID PRESCRIPTIONS, MANY INDIVIDUALS WITH PAIN NOW ENCOUNTER A TREATMENT VOID DUE TO THE LIMITED AVAILABILITY OF NON- OPIOID THERAPIES AND A SHORTAGE OF PROFESSIONALS SKILLED IN PROVIDING ALTERNATIVE TREATMENTS. ONE PROMISING SOLUTION TO THESE TWIN DILEMMAS IS THE ADVENT OF INTERNET-BASED PAIN SELF-MANAGEMENT PROGRAMS. SUCH PROGRAMS HAVE BEEN SHOWN TO IMPROVE PAIN-RELATED AND MENTAL HEALTH OUTCOMES AND TO REDUCE PROLONGED OPIOID USE. HOWEVER, SOME FACE OBSTACLES IN ENGAGING AND COMPLETING SELF-DIRECTED PROGRAMS. THESE CHALLENGES HAVE BEEN SHOWN TO DIMINISH WHEN THE SYSTEMATIC GUIDANCE OF TRAINED PROFESSIONALS IS AVAILABLE. THE RESEARCH TEAM PLANS TO CREATE A PSYCHOLOGIST/NURSE PRACTITIONER-GUIDED VERSION OF AN EXISTING, EVIDENCE-BASED ONLINE PROGRAM, THE CHRONIC PAIN MANAGEMENT PROGRAM (CPMP) TO BE DELIVERED VIA TELEHEALTH. THE RIGOROUSLY TESTED CPMP HAS DEMONSTRATED SIGNIFICANT REDUCTIONS IN OPIOID USE, PAIN SEVERITY, EMOTIONAL BURDEN, STRESS, ANXIETY, AND DEPRESSION, WHILE CONCURRENTLY ENHANCING SELF-EFFICACY, COPING SKILLS, AND KNOWLEDGE ABOUT CHRONIC PAIN AND ITS TREATMENT. DESPITE THESE SUCCESSES, THE CPMP CURRENTLY LACKS AN OPTION FOR PROFESSIONAL GUIDANCE. CONSEQUENTLY, OUR STRATEGY INVOLVES ADAPTING THE CPMP'S DELIVERY METHOD BY DEVELOPING A CURRICULUM AIMED AT TRAINING AND CERTIFYING LICENSED CLINICAL/COUNSELING PSYCHOLOGISTS (CPS) AND NURSE PRACTITIONERS (NPS) TO OFFER PROGRAM GUIDANCE. THIS MODIFIED FORMAT WILL BE INTEGRATED INTO A TELEHEALTH (VIRTUAL) TREATMENT MODEL, BROADENING THE PROGRAM'S AVAILABILITY AND ACCESSIBILITY. THE RESEARCH TEAM WILL 1) DEVELOP PSYCHOLOGIST/NURSE PRACTITIONER TRAINING MATERIALS (AIM 1), THAT ALIGN WITH THE TOPICS AND GOALS OF THE CPMP AND 2) BUILD A WEB-BASED PORTAL (AIM 2) TO HOUSE THE TRAINING PROGRAM, HOST PROFILES OF CERTIFIED CPS/NPS, PERMIT MATCHING OF CPS/NPS TO ADULTS WITH CHRONIC PAIN, PROVIDE USER ACCESS TO THE CPMP, AND GENERATE AUTOMATED REPORTS OF CLIENT PROGRAM USE/PROGRESS ON THE CPMP. FEASIBILITY WILL BE EXAMINED VIA FORMATIVE EVALUATIONS OF THE TRAINING MATERIALS AND THE PORTAL. AN ITERATIVE REVIEW AND PRODUCT REVISION PROCESS WILL BE CARRIED OUT BY 20 ADULTS WITH CHRONIC PAIN AND A PANEL OF EIGHT CPS/NPS. THESE PANELS WILL EXAMINE FACTORS SUCH AS CONTENT, USABILITY, SATISFACTION, FUNCTIONALITY, INTEREST, AND WILLINGNESS TO USE. THE GOALISTICS TEAM EMPLOYED THESE METHODS IN PRIOR PROJECTS TO CRAFT A PHASE I PROTOTYPE, PROVING ITS FEASIBILITY, TECHNICAL VALUE, AND COMMERCIAL PROMISE. IN PHASE II, WE AIM TO FORMALLY TEST THE CP/NP TRAINING/CERTIFICATION PROCESS AND COMPARE THE EFFICACY OF THE CP/NP-GUIDED CPMP TO THE SELF-DIRECTED VERSION.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 7/22/25 | ||
| Not listed | $305.9k | 7/30/24 |