Novel device for treating mitral regurgitation
Active Project Grant Awarded Last action
- Award ID
- R43HL177915
- Recipient
-
Link Medical LLC UEI T68UB63HBGZ6
- Awarding agency
-
National Heart Lung and Blood Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $596,736
Award facts
- Assistance listing
- 93.837 Cardiovascular Diseases Research
- Completion date 87% complete
- Originally
- Place of performance
- Michigan, USA
Award details come from USAspending.gov.
Description
- Abstract
- Four million people in the U.S. Are expected to be diagnosed with mitral valve regurgitation by 2030. The large majority of these patients are denied surgery and consequently faces high mortality rates. In order to address this need, the field of transcatheter heart valve therapies has produced a wide array of device concepts for treating mitral regurgitation over the past 20 years. Only one of these, edge-to-edge leaflet clipping, has reached clinical use, but with mediocre results. Link medical has invented a new approach for treating mitral regurgitation that is not derivative of any previous technologies. In patients with functional mitral regurgitation, the valve apparatus has been pulled out of its normal configuration and consequently the valve cannot close properly. The hypothesis of this project is that the impaired valve closure is due to specific pairs of mitral chords being held apart from each other. Link is developing a catheter technology that restores the valve chord positions by placing a simple constraining band around them. This concept is intended to be simpler, more robust and more effective than any existing technology. In phase i, the details of the procedure and device design will be optimized through bench testing; then a series of acute in vivo studies will be performed to demonstrate the feasibility of the procedure.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $298,368 | |
| Original award | $298,368 |
Quick answers
Who received award R43HL177915?
R43HL177915 was awarded to Link Medical LLC by National Heart Lung and Blood Institute (National Institutes of Health) on July 1, 2025.
How much is award R43HL177915 worth?
$596,736 has been obligated on R43HL177915.
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