Project Grant R43HL137540

Venarum Medical LLC received a $255,619 Project Grant award from the National Science Foundation on August 15, 2021 to support research and development activities concluding on May 31, 2022. The funding was provided through the NSF's Engineering program (CFDA #47.041), which aims to improve quality of life and economic strength through engineering innovation and excellence. Specifically, the grant supports Venarum Medical's "SBIR PHASE I: INTEGRATED MANUFACTURING OF ARTIFICIAL VALVES FOR...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $299,518 Project Grant under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to V-Flow Medical Inc. to develop a novel diagnostic catheter and modular stent system to treat pelvic venous insufficiency (PVI), a primary cause of chronic pelvic pain (CPP) in women. The project will utilize an ovine model to evaluate the safety and efficacy of V-Flow's catheter and stent system in improving clinical outcomes...

Endoshape, Inc. was awarded a $370,938 project grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to develop radiopaque shape memory polymers for neurovascular embolotherapy applications. The Cardiovascular Diseases Research program aims to support heart and vascular research, including through competitive research training grants. Under this award, Endoshape will develop new radiopaque shape memory polymer materials incorporated into embolic coils....

Corveus Medical, Inc. was awarded a $255,841 Project Grant from the National Science Foundation under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop an extravascular bipolar catheter for targeted nerve ablation with minimal collateral damage to surrounding tissues. The grant aims to support the design and prototyping of a minimally invasive, catheter-delivered venous procedure for performing extravascular greater splanchnic nerve ablation. The proposed catheter...

This Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research (CFDA 93.847) program. The $324,836 award to Flowpoint Medical Inc. aims to develop an implantable device to improve vascular access for hemodialysis patients. The device features a 3D-printed titanium shell that guides the needle to the correct insertion point, while a titanium-nitride coated valve stops...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant of $275,000 awarded to Xtract Medical Inc. aims to develop and demonstrate the feasibility of a novel catheter-based system for improved removal of blood clots during mechanical thrombectomy procedures to treat venous thromboembolism (VTE). The proposed system is designed to effectively remove large blood clots while minimizing damage to blood vessels and reducing complications such as...

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research federal grant program (CFDA 93.837) provides $738,356 to the University of Pittsburgh to develop and validate a tissue-engineered vascular graft (TEVG) device for potential clinical translation. The primary objectives are to: 1) Evaluate the TEVG constructs in vitro using industry-standard quality assessments; 2) Conduct in vivo evaluation of human-sized TEVG grafts in a...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), totaling $809,595, will fund research to evaluate the use of intravascular ultrasound (IVUS) in diagnosing and managing arteriovenous (AV) access dysfunction in end-stage kidney disease patients undergoing hemodialysis. The project aims to demonstrate the superiority of IVUS over traditional...

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) is funding research to develop a new type of bioprosthetic aortic valve made from pulmonary visceral pleura (PVP) tissue. The $742,323 award to Vanderbilt University aims to evaluate the mechanical and hemodynamic performance of the PVP aortic valve compared to existing bioprosthetic valves through in vitro experiments, computational modeling, and...

This $256,000 National Science Foundation project grant supports the development of an automated chest tube to prevent clotting. Circulatech LLC will design and prototype a novel chest tube that proactively manages fluid flow within the catheter lumen to flush and drain the tube, reducing blood clot formation. Through a process called "dilutional coagulopathy," the tube will use sterile saline or anticoagulants to reduce thrombosis in the drainage space rather than relying on...