Project Grant R43HL125477

This SBIR Phase I project, funded by the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a rapid diagnostic test for sepsis-causing pathogens in plasma samples using available digital PCR hardware. The $298,646 award to Anvil Diagnostics Inc., located in Cambridge, MA, will support the creation of a test that can comprehensively identify and quantify pathogens from small blood volumes, a critical capability for diagnosing sepsis...

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $295,895 to Ricovr Healthcare Inc. to develop a rapid, low-cost, point-of-care (POC) diagnostic platform for quantitative measurement of placental growth factor (PlGF) to predict and detect pre-eclampsia. The goal is to create an objective, affordable POC tool to improve the clinical diagnosis and monitoring of pre-eclampsia, which...

This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $318,724 to Pendar Technologies LLC to develop and test an optical probe for monitoring peripheral tissue oxygenation in critically ill neonates. The award will fund improvements to the company's resonance Raman spectroscopy-based sensor technology, which can measure tissue oxygen saturation...

This Cooperative Agreement award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $943,819 to Neocare Innovations, Inc. to develop an integrated biomedical platform and custom algorithm to optimize feeding protocols for preterm infants in neonatal intensive care units (NICUs). The project aims to create a device that uses big data on breathing patterns to quantify the synchronization of breathing and swallowing in...

The National Science Foundation (NSF) awarded a $1,250,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Prompt Diagnostics, Inc. The funding supports the development of an automated, all-in-one diagnostic test for infections caused by Treponema pallidum (syphilis) that can be used at the point-of-care. The project aims to create a portable, rapid, and affordable diagnostic platform that integrates two antibody tests, including a...

This Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to use whole genome sequencing (WGS) and diagnostic allele (DA) surveillance to study bacterial infection transmission and persistence dynamics within neonatal intensive care units (NICUs). The $881,303 award will fund research to: Determine patient, pathogen, and environment-specific factors contributing to infection...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $304,966 to Kompass Diagnostics Inc. aims to develop a portable, cost-effective diagnostic device that can rapidly detect multiple blood-based biomarkers. The key focus is on enabling rapid, quantitative measurement of reproductive hormones to support time-sensitive clinical decisions in fertility treatments. The research objectives include developing an integrated...

The National Science Foundation awarded a $275,990 Small Business Technology Transfer Phase I Project Grant to CB Enterprises of Santa Monica, California under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant funds the development of an integrated biomedical platform and custom algorithm to optimize feeding protocols for preterm infants. The platform utilizes sensors and data analytics to precisely measure infant breathing patterns during feeding, providing...

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to RT Microdx Inc. provides $274,362 to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for at-home use by non-healthcare professionals. Key technical objectives include optimizing the sensitivity of the platform's pH-sensitive polymer detection mechanism and ensuring robust performance at...

This $768,122 Project Grant from the National Institute of General Medical Sciences will support the development of statistical software to predict adverse medical events in preterm infants using multi-sensor streaming data. The awardee, William D Shannon Consulting LLC doing business as Biorankings, will develop an algorithm to transform sensor data from neonatal intensive care units into graphical representations of associations. Decision rules from statistical process control will then...