A compact, 395 GHZ traveling wave tube (TWT) amplifier for DNP-NMR and EPR spectroscopy

Ended Project Grant Awarded Last action

Award ID
R43GM142412
Recipient
Awarding agency
Obligated
$1,050,000

Award facts

Assistance listing
93.859 Biomedical Research and Research Training
Completion date
Originally
Funding
  • $700,000.00 Federal
  • $350,000.00 Non-federal
Place of performance
Framingham, MA 01702, USA

Award details come from USAspending.gov.

Description

Abstract
We propose to develop a compact, cost-effective traveling wave tube (TWT) amplifier at 395 GHZ with 1.5 w continuous wave power and 20 GHZ instantaneous bandwidth for application in dynamic nuclear polarization (DNP) enhanced solid-state and solution-state NMR and electron paramagnetic resonance (EPR) spectroscopy. With DNP, the inherently small signal intensities in a NMR experiment can be enhanced by up to two orders of magnitude. This significantly increased overall sensitivity will be highly beneficial for analytical applications of NMR spectroscopy as well as in the structure determination of BIO-macromolecules using NMR methods. Currently, DNP is performed with either low power solid-state sources (whose output power is limited to a few MW at frequencies > 300 GHZ) and at low temperatures in the range of 20-30 k (to compensate for low microwave power) or with large, gyrotron systems which can generate 50 w of power. Gyrotrons are expensive and do not possess sufficient tuning bandwidth (

Transactions

Action Federal Non-federal Date
Amendment $0 $0
Amendment $350,000 $0
Original award $350,000 $350,000

Quick answers

Who received award R43GM142412?

R43GM142412 was awarded to Bridge 12 Technologies, Inc. by National Institute of General Medical Sciences (National Institutes of Health) on September 3, 2021.

How much is award R43GM142412 worth?

$1,050,000 has been obligated on R43GM142412: $700,000 in federal funding and $350,000 in non-federal funding.

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