Project Grant R43EB039538
- The National Institute of Biomedical Imaging and Bioengineering (part of the Department of Health and Human Services National Institutes of Health) awarded $1.314 million to Massachusetts General Hospital on June 2, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop quantitative point-of-care MRI for breast cancer screening. The research addresses the limitations of current breast cancer screening modalities by...
- The National Institutes of Health National Cancer Institute awarded Albert Einstein College of Medicine $431,970 on July 1, 2026, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to refine and validate an MRI-based imaging technique for detecting tumor microenvironment of metastasis (TMEM) doorways in breast cancer. The award funds development of TMEM doorway activity-MRI (TDAM), a dynamic contrast-enhanced MRI method designed to measure vascular opening events...
- Federal Project Grant Award Summary Imagine Scientific Inc. received a $779,658 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) to advance the development and commercialization of STARLIGHT, a monochromatic x-ray imaging system designed to transform mammography. The award, effective September 1, 2025 through August 31, 2027, supports the translation of this innovative technology—the first practical, cost-effective,...
- The National Institute of Biomedical Imaging and Bioengineering awarded Rice University $182,736 on August 3, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a multi-modal, multi-depth, high-resolution micro-endoscope (M3D-HRME) for early cancer detection. The project pursues feasibility studies to create optical micro-endoscopic devices capable of detecting early-stage cancer by combining advances in...
- The National Cancer Institute awarded The Trustees of Columbia University in the City of New York $594,297 on June 18, 2026, to develop elasticity imaging methodologies for breast cancer detection and treatment monitoring under the Cancer Detection and Diagnosis Research program (CFDA 93.394). The award funds two noninvasive theranostic approaches: Harmonic Motion Imaging (HMI) for monitoring locally advanced malignant tumors during neo-adjuvant chemotherapy, and HMI-guided focused ultrasound...
- The National Cancer Institute awarded Medara, Inc. $399,860 under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on August 3, 2026, to develop a longitudinal multimodal artificial intelligence platform for personalized breast cancer screening. Medara will extend the Longitudinal Mammogram Risk (LOMAR) model framework to a large, diverse, multi-vendor dataset of over 250,000 mammograms linked with biopsy outcomes and clinical risk variables. The Phase I project comprises...
- This SBIR Phase I project, awarded by the National Science Foundation (NSF) through its Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop an innovative screening tool for early detection of breast cancer. The $305,000 award to Bired Imaging Inc. supports the efficient extraction of thermal-spatial point-cloud data from infrared images and the rapid assessment of physics-based AI algorithms to improve cancer detection, especially in women with dense breasts. The...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Johns Hopkins University $621,956 on August 12, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop artificial intelligence algorithms that detect very small pancreatic, hepatobiliary, and upper gastrointestinal cancers in computed tomography scans. The research addresses the late-stage detection problem in these disease categories, which...
- The National Institute of Biomedical Imaging and Bioengineering awarded The General Hospital Corporation (Massachusetts General Hospital) $249,000 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop engineering strategies that reduce the electromagnetic shielding burden of conventional superconducting MRI systems. The recipient will design, optimize, and experimentally validate passive and active...
- The National Institute of Biomedical Imaging and Bioengineering awarded the Regents of the University of Michigan $149,264 on March 26, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop magnetic resonance fingerprinting (MRF) technology for myocardial tissue characterization in patients with cardiac implantable electronic devices. The project addresses the clinical underutilization of cardiac MRI in CIED...
The National Institute of Biomedical Imaging and Bioengineering awarded Emai LLC $306,872 on August 20, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop an advanced microwave imaging system for early detection of breast cancer. The award is classified as a Project Grant. The recipient will address two key technical barriers in microwave breast imaging (MBI) that have delayed commercialization. Existing laboratory prototypes use only 10–20 antennas positioned around the breast, yielding insufficient measurement data for high-quality image reconstruction. Additionally, current MBI systems operate at frequencies limited to a few gigahertz, restricting spatial resolution to the centimeter level—inadequate for detecting small tumors near breast tissue. The project aims to overcome these limitations to transition MBI from laboratory prototype to a market-ready clinical product. MBI employs non-ionizing radiation with dielectric contrast between cancerous and healthy breast tissue 0.1–10 times larger at microwave frequencies, with radiation exposure equivalent to or less than a wireless phone call, positioning it as a potential replacement for X-ray screening. The period of performance runs from August 20, 2026, through August 19, 2027. Work is performed in Laurel, Maryland.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.9k | 8/18/26 |