Project Grant R01CA301199
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Trustees of Columbia University in the City of New York a Project Grant of $531,825 under the Cancer Biology Research program (CFDA 93.396) effective August 1, 2025, with completion targeted for July 31, 2030. This research initiative focuses on understanding the molecular mechanisms of castration sensitivity in prostate epithelium, with the ultimate goal of improving therapeutic responses to androgen-deprivation therapy...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded Columbia University's Herbert Irving Comprehensive Cancer Center (HICCC) a $193,926 Project Grant under the Cancer Treatment Research program (CFDA 93.395) effective September 1, 2025, through August 31, 2030. This award supports the development and implementation of investigator-led clinical trials within the NCI Clinical Trials Network (NCTN), Experimental Therapeutics Clinical Trials Network (ETCTN), and NCI Community...
- Federal Grant Award Summary Albany Medical College received a $648,579 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) for the period June 1, 2026 through May 31, 2031. The award supports research investigating how tumor biomechanics and the tumor microenvironment influence monoclonal antibody drug delivery and receptor engagement in HER2-positive breast cancer treatment. The project will utilize xenograft and...
- Federal Grant Award Summary The National Cancer Institute awarded The Trustees of Columbia University in the City of New York a $1,276,947 Project Grant under the Cancer Treatment Research program (CFDA 93.395) effective August 1, 2025, with a completion date of May 31, 2030. The project focuses on modulating the localization and persistence of microbial neoantigen vaccine vectors to enhance therapeutic efficacy in cancer immunotherapy. The research will investigate how bacterial vectors, such...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $683,970 Project Grant to Columbia University's Health Sciences Division effective April 1, 2026 through March 31, 2031, under the Cancer Treatment Research program (CFDA 93.395). This research project focuses on developing and evaluating therapeutic approaches to treat pancreatic ductal adenocarcinoma (PDAC) through stromal modification and immune modulation. The research investigates the role of αvβ5 integrin in PDAC...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded a Project Grant of $102,984 to The Trustees of Columbia University in the City of New York (Health Sciences Division) on December 25, 2025, under the Cancer Research Manpower program (CFDA 93.398). The award, with an ultimate completion date of June 30, 2028, supports research titled "Spatiotemporal Resolution of Niche and Genomic Co-Evolution in Brain-Metastatic Organotropism." The project aims to...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded Johns Hopkins University a $144,193 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) effective September 4, 2025 through August 31, 2030. This award provides protected salary support for Dr. Preethi Korangath to serve as a Laboratory Research Specialist in Dr. Robert Ivkov's laboratory, where she will facilitate the completion of Research Project Grants (R01) by leveraging her expertise...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded a Project Grant of $627,148 to the University of Maryland, College Park on August 5, 2025, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop an image-guided ethyl cellulose ethanol ablation therapy for treating cervical dysplasia in low and middle-income countries (LMICs). The project, extending through July 31, 2030, builds upon prior Small Business Innovation Research (SBIR) funding...
- Federal Grant Award Summary The National Cancer Institute awarded a $409,141 Project Grant to the University of California, Davis under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) for the period June 1, 2026 through May 31, 2028. The project focuses on developing and validating contrast-enhanced perfusion computed tomography (CT) as an alternative diagnostic imaging methodology for liver radioembolization treatment planning. Currently, patients undergoing selective internal...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded Columbia University's Health Sciences Division a $501,422 Project Grant under the Cancer Biology Research program (CFDA 93.396) commencing May 1, 2026, with completion targeted for April 30, 2031. This award supports fundamental research to advance understanding of synthetic lethal (SL) vulnerabilities in specific cancer subtypes, with the ultimate objective of developing novel precision oncology therapeutics. The research...
The National Cancer Institute awarded The Trustees of Columbia University in the City of New York $594,297 under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop and validate noninvasive elasticity imaging methodologies for breast cancer treatment monitoring and ablation. The project, which commenced June 18, 2026 and concludes May 31, 2031, focuses on two integrated theranostic approaches: (1) Harmonic Motion Imaging (HMI) for monitoring locally advanced breast cancer patient response to neo-adjuvant chemotherapy by mapping tumor stiffness changes, and (2) HMI-guided Focused Ultrasound (HMIGFUS) for thermal ablation treatment of benign and non-metastatic tumors while simultaneously monitoring treatment efficacy. Both methodologies employ a single ultrasound beam that operates at low power for diagnostic vibration and tissue characterization or at high power for therapeutic ablation without interrupting treatment delivery. The research will be conducted at Columbia University's Health Sciences Division facility in New York, NY, with animal model studies designed to establish the safety and efficacy of these imaging-guided treatment techniques prior to clinical translation. This project directly supports the Cancer Detection and Diagnosis Research program's objectives to improve diagnostic techniques, predict disease course and treatment response, and develop accurate methods for monitoring therapeutic effects in cancer patients.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $594.3k | 6/19/26 |