This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $704,672 to Flowpoint Medical Inc. to develop an implantable self-sealing needle guide system to improve vascular access and safety for hemodialysis patients. The award will fund the refinement of the device's manufacturability and operational parameters, as well as a large animal...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $350,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Katharos, Inc., a for-profit woman-owned business based in Denver, Colorado. The goal of this 1-year project is to develop and evaluate a novel extracorporeal device called the "PhosFilter" that can enhance phosphate removal from the blood of patients undergoing hemodialysis for...
This $518,661 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to advance the design of hemodialysis cartridges beyond the focus on urea removal. The project will test a novel parallel-plate dialyzer design that controls shear forces to potentially reduce platelet activation and clotting risks for the 548,000 Americans who rely on dialysis. The award to Vanderbilt...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $299,999 Project Grant (CFDA 93.847) to Hibar Microsciences, LLC to develop a prototype for CLEAR, a novel hemodialysis cartridge designed to improve the clearance of protein-bound uremic toxins (PBUTs) from the blood of patients with end-stage renal disease. The key objectives are to: 1) Develop a method for immobilizing lipocalin proteins onto dialysis membrane matrices to enhance PBUT removal; 2) Create and...
This Project Grant award of $550,000 from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program will fund the development of a catheter monitoring system to reduce peritoneal dialysis (PD) infections. The project, led by The Johns Hopkins University, aims to develop a medical device that enables real-time, continuous, and quantitative monitoring of biomarkers relevant to PD-associated infections. This will involve optimizing the optical and flow...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $298,371 to Anova Biomedical, Inc. to develop a new class of biodegradable and elastic vascular grafts for hemodialysis. The funding will be used to refine manufacturing techniques for these grafts, which are designed to closely resemble the mechanical properties of native vasculature and slowly remodel into...
This Project Grant award of $3,740,270, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports the development and evaluation of a subnormothermic (room temperature) oxygenated perfusion platform for extended preservation of high-risk kidney grafts. The awardee, Biomedinnovations, Inc. (BMI), is collaborating with investigators at the Duke Ex Vivo Organ Lab...
This $1,470,094 project grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) will fund research by New York University School of Medicine to optimize pre-implantation kidney transplant biopsy interpretation using artificial intelligence (AI) assistance. The key products and services to be delivered under this 5-year project include: Developing a comprehensive unbiased atlas of histopathology in pre-implantation deceased donor kidney biopsies using...
This $2,252,419 Cooperative Agreement award, funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports the development of an innovative vascular conduit device for dialysis vascular access. The award brings together industry and academic partners to create the "Functional Integrated Electrospun (FINE)" device, which comprises an inner...
The federal Project Grant award R43DK137616 for $275,766.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds Biosurfaces Inc., a for-profit medical device company, to develop and evaluate an implantable, electrospun cell chamber device loaded with human pancreatic islets. The device aims to provide an immune-protected environment to support...