The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $619,347 Project Grant (CFDA 93.121 - Oral Diseases and Disorders Research) to Light Research Inc., a small business in Tucson, Arizona, to optimize and commercialize a compact multimodal intraoral camera. This innovative device integrates polarized white light imaging, autofluorescence imaging, optical coherence tomography, and near-infrared transillumination modalities to improve the sensitivity and specificity in...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121) aims to develop an intraoral camera system that can detect and monitor early-stage dental caries (tooth decay) using targeted fluorescent nanoparticles and artificial intelligence (AI) software. The $294,632 award to Greenmark Biomedical Inc. will fund the development and optimization of a minimally viable product...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research Program (CFDA 93.121), will develop a new class of anti-caries therapy that targets pathogenic oral microbes to reverse oral dysbiosis and eliminate early childhood caries (ECC). The $3,471,873 award, with a performance period from September 2024 to June 2029, will take a multiscale approach to create fluoride efflux inhibitors that potentiate the...
This $1,297,941 federal Project Grant award, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop a novel platform for rapid and precise creation of bioactive, multifunctional dental restoration materials. The key products and services being delivered through this grant include: Creating a self-improving dental adhesive that enhances its bond to tooth structure by facilitating...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $421,800 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Midwestern University. The purpose of this 3-year grant, with a start date of September 7, 2023, is to develop hybrid hydrogel-based dental adhesives that are less vulnerable to hydrolytic degradation compared to current methacrylate-based alternatives. The goal is to create a truly biomimetic dental adhesive that can not only...
The National Institute of Dental and Craniofacial Research (NIDCR), through its Oral Diseases and Disorders Research program (CFDA 93.121), awarded a $295,689 Project Grant to Callentis Consulting Group LLC, a woman-owned small business, to develop high-performance, bisphenol A (BPA)-free dental restoration composites with remineralization capabilities. The research, conducted in collaboration with the University of Colorado and New Mexico State University, aims to create innovative...
This $162,216 Federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to investigate microbe-microbe interactions within the oral microbiome at the single-cell level. The key products and services to be delivered through this award include: Developing an approach that combines multiplex FISH imaging with expansion microscopy to study the spatial organization and functional...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $1,178,476 to Oraliva, Inc. to develop an AI-linked cytomics-on-a-chip tool for identifying and managing oral lichenoid lesions in primary care settings. The key products to be delivered include: 1) designing and producing alpha instrumentation units for research and commercial use, 2) defining optimal...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to T33 Dental, Inc. in Cambridge, MA aims to validate a novel device and approach for enhancing the delivery of pharmaceuticals and cosmetics into human teeth. The project seeks to demonstrate the technical feasibility of electrically-mediated electrokinetic flow to enable deeper and more rapid delivery of clinically relevant molecules, such as fluoride and hydrogen...
This National Institute of Dental and Craniofacial Research (NIDCR) Oral Diseases and Disorders Research (CFDA 93.121) Project Grant award to East Carolina University (ECU) aims to develop innovative dental materials that can inhibit the formation of harmful bacterial biofilms while preserving beneficial oral bacteria. The $164,255 grant will fund research to synthesize a new antimicrobial agent, formulate it into methacrylate-based self-etch adhesive (SEA) dental materials, and evaluate the...