This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant of $274,999 awarded to Materialize Bio, Inc. focuses on developing a novel manufacturing approach for biopolymer-based implantable medical devices, specifically bioengineered tympanostomy tubes. The project aims to create degradable, biocompatible, and antimicrobial tympanostomy tubes using an innovative process involving 3D printed molds, centrifugation, and polymerization. This...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA Program 93.173 "Research Related to Deafness and Communication Disorders" is focused on developing innovative diagnostic imaging methods for otitis media, a common childhood condition. The $726,079 award will support research conducted by The Leland Stanford Junior University to create three advanced optical imaging techniques: 1) shortwave infrared fluorescence...
This $498,000 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research to develop an ex-vivo porcine round window membrane (RWM) model and evaluate nanovesicles for enhanced, non-surgical delivery of therapeutics into the inner ear. The primary objectives are to: 1) validate the porcine RWM model for drug permeability, 2) identify...
The federal Project Grant award R01DC021954, totaling $581,105.00, was granted by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant supports research to develop natural-based therapies for preventing aminoglycoside-induced hearing loss, a significant health concern affecting 40-60% of patients receiving this common antibiotic treatment. The research, conducted by...
This federal Project Grant award of $722,677, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), is aimed at improving the diagnosis and understanding of otitis media with effusion (OME) and its related hearing loss in children. The primary objectives are to: 1) develop a non-invasive objective estimate of hearing loss due to OME, 2) characterize the short-term...
This $305,197 Project Grant awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) aims to develop a novel medical device called PHONOCATH. The device is designed to provide a minimally invasive, patient-friendly approach to diagnosing pulsatile tinnitus, a form of tinnitus characterized by a heartbeat-synchronous sound that can lead to severe depression or anxiety in 60%...
This federal Project Grant award of $1,022,655 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under CFDA Program 93.173 - Research Related to Deafness and Communication Disorders, supports the development of a minipig model for evaluating drug pharmacokinetics and implantable device development for inner ear research. The grantee, Turner Scientific LLC, a small disadvantaged business, will validate standard measures of drug efficacy and safety in normal and...
The Project Grant award R43DC021615 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders Federal Grant Program (CFDA 93.173). The $275,371 award to Auricle Health Inc. in Oakland, CA will fund the development of an extracochlear device to restore high-frequency hearing for patients with sensorineural hearing loss, a condition affecting over 460 million people worldwide. In Phase I, the...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Federal Grant Program "Research Related to Deafness and Communication Disorders" (CFDA 93.173), will support research using optical coherence tomography (OCT) to visualize the fluid compartments of the human inner ear. The $701,848 award will be used to characterize the normal endolymph-to-perilymph ratio in control subjects, and compare it to subjects with Meniere's...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $674,021 to the Massachusetts Eye and Ear Infirmary to advance the development of an implantable microphone technology for totally-implantable cochlear implants (TICI). The project aims to refine and test a novel implantable microphone design called the UMIC, which senses motion of...