Project Grant R43CA176892

This National Science Foundation (NSF) Engineering grant award, under the CFD Program 47.041, provides $150,000 to the University of Georgia Research Foundation to develop novel methods for high-throughput, antibody-free cell sorting. The project, titled "EAGER: IMPRESS-U: HIGH-THROUGHPUT AGILE INTERFACES FOR CELL SORTING," aims to create an alternative, scalable approach to efficiently separate therapeutic cells from unwanted or damaged cells for biomedical applications. The...

Floating Island International, Inc. was awarded a $183,395 project grant from the Department of Energy Office of Science under the Office of Science Financial Assistance Program (CFDA 81.049) to advance the development of floating solar-powered nanobubble aeration systems for use with floating treatment wetlands. The award, issued on June 28, 2021 for a period of one year, will support efforts to deliver innovative floating infrastructure utilizing solar power and nanobubble technology to...

Partillion Bioscience Corp. was awarded a $659,037 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences to develop reagent products enabling high-throughput screening and selection of single cells based on secreted bio-products. Under the Biomedical Research and Research Training program (CFDA 93.859), Partillion plans to transition its lab-on-a-particle technology—highlighted as a 2020 SLAS Innovation Award winner—into the first reagent product...

Aquaculture System Technologies, L.L.C. (AST) received a $169,892 Small Business Innovation Research (SBIR) Phase I Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture to develop "start-up" beads for fixed film biological reactors. The beads are designed to eliminate losses during the acclimation period by stimulating heterotrophic bacterial growth for 3-4 weeks without rapidly increasing dissolved biodegradable concentrations....

This Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) will develop a novel membrane separation technology to address the energy-efficient separation of small molecules from industrial process streams for a range of industries. The $275,000 award to Avanpore LLC, a for-profit limited liability company located in Woburn, MA, will run from October 1, 2024 to March 31, 2025. The project aims to create functionalized...

This $337,863 Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049) supports research by Professor Ken Marcus and his team at Clemson University to develop new methods for isolating and purifying diverse biological nanoparticles, including exosomes, lentiviruses, and adeno-associated viruses. The researchers aim to characterize and implement a unique fiber-based stationary phase,...

This $902,504 cooperative agreement from the National Science Foundation Division of Industrial Innovation under the Engineering program (CFDA 47.041) supports the development of a scalable downstream purification process for gene therapy vectors by Isolere Bio, Inc. of Durham, North Carolina. The non-chromatographic method seeks to address current inefficiencies that lead to single digit yields by utilizing a polypeptide-based reagent combining affinity capture with phase separation and...

This $230,000 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) aims to advance the understanding of how soft, deformable particles such as oil droplets and cells move through complex environments. The Research Foundation of the City University of New York (RFCUNY) at the City College campus is leading this collaborative research project, which combines carefully designed experiments with advanced computer simulations. The goal is to develop...

Zaiput Flow Technologies LLC received a $275,000 Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop an innovative, continuous crystallization device for pharmaceutical manufacturing. The goal is to improve the purification process of active pharmaceutical ingredients, which is a critical step used in over 90% of pharmaceutical production. The novel device aims to address scalability, cost, and...

Dynaflow, Inc. received a $199,754 Project Grant award from the Department of Energy Office of Science on June 27, 2022 to support research titled "CAVITATION ENHANCED SUBCRITICAL WATER EXTRACTION OF WET ALGAE FOR PHYTOL AND LIPIDS RECOVERY." The award is being carried out in Jessup, Maryland through March 26, 2023. The funding supports Dynaflow's research under the Office of Science Financial Assistance Program (CFDA #81.049), which aims to transform understanding of nature and...