Project Grant R43AG097205
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $684,924 to Northwestern University to conduct research on the relationship between the noradrenergic (NA) system, sleep quality, and cognitive function in older adults with insomnia. The project aims to systematically characterize central and peripheral measures of the NA system and assess their association with sleep quality and cognitive performance in older adults with insomnia, as well as...
- The National Institute on Aging (NIA) awarded a $780,466 Project Grant (CFDA 93.866 Aging Research) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver, with a period of performance from December 15, 2024 to November 30, 2029. The goal of this project is to develop digital biomarkers using single-channel sleep electroencephalography (EEG) to monitor brain health and detect pathological aging and early neurodegenerative changes, such as those seen...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $506,399 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to Healthy Design LTD. CO. to develop a novel continuous predictive wearable agitation monitor and alert system using actigraphy and AI for hospitalized older adults. The goal is to prevent delirium and dementia by closely monitoring agitation levels and enabling timely implementation of non-harmful...
- The National Institute on Aging (NIA) awarded Brigham & Women's Hospital Inc. a $2,576,936 Project Grant under the Aging Research federal grant program (CFDA 93.866) to characterize the variability in sleep spindle activity across a population and evaluate the use of sleep spindle dynamics as biomarkers for Alzheimer's disease, mild cognitive impairment, and trisomy 21. The 3-year project will develop statistical models and methods to analyze sleep spindle patterns and their relationship...
- The National Institute on Aging (NIA) awarded a $1,010,368 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Koronis Biomedical Technologies Corp. (KBT) to develop and validate an interactive gaming platform to facilitate cognitive interventions for individuals living with mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (AD/ADRD). The goal is to create an in-home cognition training system that provides evidence-based cognitive activities...
- This federal Project Grant award of $125,000.00, provided by the National Institute on Aging (CFDA 93.866 Aging Research), supports research to investigate the relationship between sleep loss and neurodegeneration. The grantee, The Washington University, will use the funding to examine how sleep deprivation can epigenetically alter microglial responses to tau protein aggregates, which is a key pathological feature of Alzheimer's disease and other tauopathies. The research aims to identify...
- The National Institute on Aging (CFDA 93.866 - Aging Research) awarded a $433,125 project grant to the University of California, Los Angeles (UCLA) to develop and evaluate a culturally adapted sleep intervention program for older Korean immigrants with poor sleep. The 2-year project aims to refine an existing cognitive behavioral therapy for insomnia (CBTI) program to better address the cultural influences on sleep habits of this population. In Year 1, UCLA will work with stakeholders to adapt...
- The National Institute on Aging (NIA), under the Federal Aging Research program (CFDA 93.866), awarded a $245,148 project grant to Eyenexo LLC to develop an automated rodent behavior testing system for non-invasively assessing early-stage Alzheimer's disease (AD). The project aims to develop a behavior biomarker that can differentiate AD from normal aging by studying defensive behaviors triggered by looming stimuli, which are linked to early AD pathology in the midbrain region. The 2-year...
- The National Institute on Aging (NIA) awarded Hido Technologies, Inc. a $1,240,765 Project Grant (CFDA 93.866 - Aging Research) to develop an internet-connected, self-medicating device with video direct observed therapy (VDOT) capabilities. The goal is to improve medication adherence and cognitive outcomes for persons with Alzheimer's disease and related dementias (AD/ADRD), while also reducing caregiver burden and healthcare costs. The device, called Homecare, integrates with a novel pharmacy...
- The U.S. National Institute on Aging (NIA) awarded a $1,089,329 Project Grant to Homecare Hub US Inc. under the Aging Research Federal Grant Program (CFDA 93.866) to scale a network of small community-based care homes as a high-value alternative to institutional long-term care. The project aims to demonstrate improved health outcomes for seniors by leveraging a technology platform that facilitates personalized, cost-effective care through a decentralized network of 2-12 person residential care...
The National Institute on Aging (NIA), via the Aging Research Federal Grant Program (CFDA 93.866), awarded a $499,963 project grant to Proactive Life Inc. on September 20, 2025. The project, titled "An Internet of Things Automated Cognitive Behavioral Therapy for Insomnia that Improves Cognition in Older Adults," will validate a fully automated version of Proactive Life's patented technology to improve adherence to cognitive behavioral therapy for insomnia (CBTI) in older adults. The new "SleepSpace AI" system will use smart devices, voice commands, and personalized feedback to increase engagement with CBTI and measure its impact on sleep quality and cognitive function. The project aims to address the significant public health burden of insomnia and Alzheimer's disease, which collectively cost the U.S. healthcare system over $800 billion annually.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $500.0k | 9/18/25 |