Establishing the market-readiness of an in vivo technology for assessing drug toxicity-induced tissue damage
Active Project Grant Awarded Last action
- Award ID
- R42GM140538
- Recipient
-
Durametrix LLC UEI KACSQ7VNS1L7
- Awarding agency
-
National Institute of General Medical Sciences
National Institutes of Health, Department of Health and Human Services
- Obligated
- $2,969,802
Award facts
- Assistance listing
- 93.859 Biomedical Research and Research Training
- Completion date 90% complete
- Originally
- Place of performance
- Oak Creek, WI 53154, USA
Award details come from USAspending.gov.
Description
- Abstract
- There is a substantial and growing need for in vivo toxicity testing, as in drug r & d IT is critical to be able to understand toxicity and to identify and eliminate overly toxic candidates. We developed an imaging-based approach that detects toxicity-induced tissue injury in a minimally invasive, whole body and dynamic fashion. The goal of the current phase II sttr grant is to expand the marketability and market readiness of the technology by demonstrating a broadened scope of utilities including semi-quantitative characterization and drug safety. Overall, this in vivo imaging approach identifies an important marker for drug toxicity on a personalized basis with objective and quantitative metric. The early detection of drug toxicity in susceptible tissues will help make timely decisions in drug r & d by prioritizing safe and efficacious candidates. The technology is applicable to multiple stages in pharmaceutical r & d and is expected to generate a significant impact on drug development and drug safety.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $946,480 | |
| Amendment | $1,011,661 | |
| Original award | $1,011,661 |
Quick answers
Who received award R42GM140538?
R42GM140538 was awarded to Durametrix LLC by National Institute of General Medical Sciences (National Institutes of Health) on February 2, 2021.
How much is award R42GM140538 worth?
$2,969,802 has been obligated on R42GM140538.
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