Project Grant R42AG094389
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $499,686 to support the development of the Momento smartphone app. The app aims to transform regular photo activities into a way to continuously monitor cognitive function and detect early signs of memory changes in older adults. Key goals of the 1-year project include: 1) Testing how 200 older adults use and enjoy the app, ensuring it is engaging for regular use; and 2) Verifying the system can...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $474,092 Project Grant under the Aging Research federal grant program (CFDA 93.866) to One Health Studio LLC in San Francisco, CA. The grant supports the development and evaluation of the "FLOURISH ALL" platform, an AI-enabled digital health solution aimed at reducing Alzheimer's disease and related dementia (ADRD) risk in midlife women through stress management and promotion of...
- This $114,498 Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) will fund a study to investigate the construct validity of smartwatch-derived metrics for early detection of Alzheimer's disease and related dementias. The study will recruit a diverse sample of 90 participants aged 55 and older with healthy cognition or mild cognitive impairment from the Philadelphia region. Participants will wear a Garmin Vivosmart 4 smartwatch for 30 days to passively monitor...
- This $399,813 Project Grant award from the National Institute on Aging (NIA), under the Aging Research grant program (CFDA 93.866), supports the development of WHIM (Women's Health in Menopause), a digital health product designed to improve the menopause-related experience for midlife women. The project extends an existing digital behavioral intervention platform, GEMINI, to create WHIM, which will incorporate the MENOGAP patient education program and enhance the platform with additional...
- This Project Grant award of $1,006,653 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Posit Science Corp. supports the "IMPROVING NEUROLOGICAL HEALTH WITH ACETYLCHOLINE VIA NEUROPLASTICITY-BASED COMPUTERIZED EXERCISE IN MILD COGNITIVE IMPAIRMENT (INHANCE-MCI)" program. The project aims to deploy a computerized cognitive training program that integrates validated exercises to potentially reduce the long-term risk of dementia onset in individuals with mild...
- This $4,765,698 federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will fund a research study by the University of California, Santa Barbara to investigate the effects of endocrine aging on spatial navigation ability and its neuronal systems. The project will enroll 240 cognitively normal midlife adults, with a balanced distribution of pre-, peri-, and post-menopausal women, and use immersive virtual environments and brain imaging to elucidate how...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) aims to evaluate the utility of self-reported subjective cognitive concerns (SCC) as an early screening tool for Alzheimer's disease (AD). The $336,000 award will support research to: 1) assess the longitudinal relationship between baseline pen-and-paper measures of SCC and subsequent plasma AD biomarkers, 2) examine whether baseline smartphone-based ecological momentary assessment (EMA) SCC measures...
- This $880,000 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will fund a study to examine the effects of daily stress, sleep, and sex hormones on accelerated vascular aging in premenopausal midlife women. The 2-year study, starting November 2024, will investigate how emotional reactivity to daily stressors and sleep variability contribute to vascular dysfunction prior to menopause, and how these factors interact with changes in estradiol levels. The...
- The National Institute on Aging (NIA), through its Aging Research Federal Grant Program (CFDA 93.866), awarded a $499,778 project grant to S-3 Research LLC to co-design a mobile tool to improve diversity and inclusivity in Alzheimer's Disease and Related Dementias (ADRD) clinical trial participation. The project aims to leverage digital approaches, including mobile, website, and artificial intelligence chatbot features, to enhance the education, recruitment, and enrollment of older adults in...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $885,006 to Brigham & Women's Hospital Inc. to develop a smartphone-based point-of-care diagnostic system for detecting Alzheimer's disease-related biomarkers in blood plasma. The system will utilize microfluidics, nanotechnology, optical sensing, and deep learning to measure amyloid-beta, phosphorylated tau, and neurofilament light chain within 30 minutes, with the goal of creating an...
This $399,999 project grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) aims to further develop and test a novel, passive, and unobtrusive smartphone-based tool called SKYE for assessing cognitive function in peri- and post-menopausal women. The project has three key objectives: 1) cross-platform development of the SKYE tool, 2) testing the feasibility and usability of SKYE through focus groups, and 3) validating the SKYE cognitive score against gold-standard neuropsychological and neuroimaging assessments, as well as evaluating its sensitivity to detect cognitive changes related to sleep disturbances and vasomotor symptoms in the target population. Successful completion of this project will provide evidence for the utility of SKYE in addressing the significant unmet needs and economic burden associated with cognitive dysfunction in menopausal women.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $400.0k | 9/11/25 |