Project Grant R41MH142265
- The National Institute of Mental Health (NIMH) awarded a $505,311 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Intelligent Imaging Innovations, Inc. (3i), a for-profit manufacturer of advanced microscopy equipment and software based in Denver, Colorado. The two-year grant, awarded on January 1, 2025, seeks to establish the feasibility of combining recent advances in optical techniques to produce a commercial instrument that enables large-scale, all-optical...
- This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is for the development and commercialization of an automated platform for high-throughput behavioral and electrophysiology research in freely behaving rats. The $1,266,318 award to Spikegadgets, Inc., a neuroscience research equipment company based in San Francisco, CA, will fund the creation of an integrated system that can administer operant...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $659,217 to develop a novel microelectrode sensor to continuously measure endogenous neuropeptide Y (NPY) release in brain tissue and single cells. The primary objective is to enhance detection of NPY, a key neuropeptide implicated in neurological disorders, by optimizing an existing NPY biosensor to improve sensitivity and selectivity while...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), aims to develop an integrated, portable sensor suite for concurrent recording of neural activity, physiological arousal, motor signals, and physical interactions in social environments. The $1,453,943 award will fund research to integrate neural oscillatory features of visual attention with additional sensors to extract physiological and movement-derived...
- The National Institute of Mental Health (NIMH) awarded a $314,113 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Physical Sciences Inc. (PSI) of Andover, MA. The grant will fund the development and demonstration of a high-speed, multicolor confocal fluorescence imager to simultaneously capture multi-wavelength signals and display them as separated or merged multicolor images and 3-D stacks. This technology innovation will enable mapping of complex neuronal network...
- The National Institute of Mental Health (NIMH) has awarded a $992,826 Project Grant (R44MH135529) to Blackrock Microsystems, Inc. to develop the "OA2" - a high-density chronic optogenetic interface for primate brain research. The goal of this Small Business Innovation Research (SBIR) Phase I project is to engineer a new two-level optogenetic stimulation device that combines Blackrock's "Utah Optrode Array" technology with a surface-level stimulation array. This will enable...
- The National Institute of Mental Health (NIMH) awarded a $1,596,935 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Petcoil, Inc., a for-profit company based in Sunnyvale, California. The grant, awarded on March 11, 2025, with a planned completion date of February 29, 2028, supports the commercialization of a portable, brain-dedicated Positron Emission Tomography (PET) insert system that can be integrated with existing Magnetic Resonance Imaging (MRI) machines....
- This Project Grant award of $517,546, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to optimize, benchmark, and validate a novel multimodal microelectrode array (MEA) probe that integrates fast-scan cyclic voltammetry (FSCV) for sub-second neuromodulator sensing with parallel electrical recording. The research team, led by investigators from Dartmouth College, aims to develop this integrated MEA platform...
- This $499,781 project grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will develop a multi-functional "ORGANOID-CRADLE" interface to measure and modulate the activity of neural organoid cultures. The ORGANOID-CRADLE will include a multi-electrode array (MEA) and light-emitting diodes (LEDs) for optogenetic experiments, with a revolutionary soft robotic structure to grip non-adherent organoid cultures and...
- This federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $416,925 to Objective Biotechnology, Inc. to develop and evaluate a miniature, high-performance microscope system for imaging brain activity in freely behaving mice. The award period runs from September 15, 2025 to August 31, 2027. The key objectives are to engineer the "Mini-MScope" device with a highly sensitive imaging sensor, evaluate its...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $394,708 to Carolina Instruments, Inc. to develop and improve a novel Biometric Ocular Photometry (BOP) system for simultaneously tracking pupil size, heart rate, and respiratory rate in freely moving animal models. The BOP technology leverages photoplethysmography techniques to enable real-time physiological monitoring with minimal impediment to animal behavior, addressing limitations of current "gold standard" methods. The goals of this 1-year project are to optimize the BOP hardware and data processing to prepare the system for clinical translation and broader scientific research applications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $394.7k | 9/8/25 |