This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $350,000 in funding to Sinopia Biosciences Inc. for the development and validation of data standards and computational methods for large-scale metabolomics data analysis to support data-driven drug discovery.
The key products and services to be delivered include: 1) Developing computational methods for generating...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $733,376 to the Georgia Tech Research Corp to develop and apply new predictive medicine technology for identifying disease causes, developing cures, and optimizing patient care.
The key products and services being delivered under this 5-year grant include: 1) integrating biomedical literature and data to create a comprehensive...
The National Institute of General Medical Sciences (NIGMS) awarded a $385,700 Project Grant (CFDA 93.859 Biomedical Research and Research Training) to the University of Pittsburgh to develop and evaluate novel computational approaches for pharmacogenomics research on complex diseases. The 5-year project aims to: 1) devise advanced deep learning models that integrate multi-omic data to predict the molecular and phenotypic effects of genetic and chemical perturbations in disease models; 2)...
Quantum Simulation Technologies Inc., doing business as Qsimulate, received a $442,362 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences to develop and validate a novel high-performance implementation of density functional theory quantum mechanics for scoring ligand-protein interactions. The award was made under the Biomedical Research and Research Training program (CFDA 93.859), which supports basic research that increases understanding of...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $350,000 in funding to Koliber Biosciences Inc. to develop an artificial intelligence (AI)-based platform for optimizing the development of therapeutic peptides. The platform will focus on encoding non-canonical amino acids and cyclic peptides, as well as demonstrating high-performance machine learning on commercial peptide...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $591,842 to 3D Molecular Designs LLC to develop two applications leveraging machine learning and object detection technology. The first application will provide augmented reality-based feedback to students on their modeling of protein structures using 3D Molecular Designs' Mini-Toobers modeling tools. The second application will...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $306,872 to Simulations Plus Inc. to develop an improved 3D ligand-matching methodology that incorporates water molecules when comparing potential drug compounds. The goal is to create a program that accounts for water-mediated protein-ligand interactions, which can result in false negatives when using current shape-matching...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,739,977 Project Grant (CFDA 93.859 Biomedical Research and Research Training) to Eclipse Bioinnovations, Inc. to develop the "EMOA: A Multi-Omic Service for Mechanism of Action Determination in Drug Screening" platform.
The EMOA platform will combine transcriptomics and translatomics to rapidly identify and screen candidate drug compounds, with the goal of shortening the drug discovery research cycle for biotech...
The National Institute of General Medical Sciences (NIGMS) awarded a $258,586 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to MSTM LLC, located in Newark, DE. The purpose of this 12-month Phase I project is to demonstrate the feasibility and proof-of-concept of a new surface reader technology that can remotely detect and analyze the molecular composition of surfaces, including for the early detection of infectious diseases, hazardous materials, and...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $365,630 to Wayne State University to support the development and application of multiscale models for the rational design of complex biomolecules, including nucleic acid-based imaging agents and carbohydrate-based drugs. The project aims to automate the creation of large, high-quality datasets with accurate simulations, and...