Project Grant R41DA049390

This $5.37 million project grant from the National Institutes of Health National Institute on Drug Abuse will fund the development of a context-aware digital adherence intervention called SMARTSTEPS to improve pre-exposure prophylaxis (PrEP) adherence among men who have sex with men with substance use disorder. The grant will support two phases. Phase I will inform the specification of an algorithm that utilizes digital phenotyping data from a smartphone app to anticipate non-adherence based...

The National Institute on Drug Abuse (NIDA) awarded a $2,729,018 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Rhode Island. The purpose of this 2-year award, with a start date of September 15, 2024, is to rigorously develop and evaluate a mobile health intervention for adults with co-occurring opioid use disorder (OUD) and post-traumatic stress disorder (PTSD) during community re-entry after residential OUD treatment. The proposed mobile app...

This Project Grant from the National Institute on Drug Abuse, part of the Department of Health and Human Services, provides $738,086 to Brown University under the Drug Abuse and Addiction Research Programs (CFDA 93.279) to evaluate a technology-assisted parenting intervention for adolescents in residential substance use treatment. Specifically, the funding supports a randomized controlled trial to test the effectiveness of Parent SMART, a mobile app and telehealth coaching program that...

Ksana Health Inc. received a $812,902 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and refine the VIRA mobile application platform. Awarded on July 15, 2025, with completion targeted for April 30, 2026, this Phase I Small Business Innovation Research (SBIR) grant supports technical development and user-centered research to extend VIRA's capabilities for delivering just-in-time adaptive...

Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Trustees of Columbia University in the City of New York a $581,543 Project Grant on April 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a clinical trial of the Sense2Quit mobile health application for smoking cessation. The research deliverables include enhancement of the app's technical capabilities—specifically improving machine learning-based smoking gesture detection...

Federal Project Grant Award Summary Rescue Biomedical, LLC received a $799,430 Phase I Small Business Innovation Research (SBIR) Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) for the period of August 1, 2025 through July 31, 2026. The company is developing the Automatic Detection Device (AD2), a user-centric wearable overdose detection module designed as the initial commercialization phase of its broader Automatic...

Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Massachusetts General Hospital $395,280 under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and evaluate AMP-C, a digital therapeutic (DTX) intervention targeting reward dysfunction in individuals with co-occurring Cannabis Use Disorder (CUD) and Major Depressive Disorder (MDD). This five-year project grant, effective July 1, 2025 through June 30, 2030, delivers a user-centered digital...

This $424,545 Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) will support a national survey on naloxone use and access. The survey, conducted by the RAND Corporation, will provide critical, timely evidence on the state of naloxone carrying and purchasing behavior in the U.S., including the impact of recently approved over-the-counter naloxone products. The project will monitor knowledge, barriers, and willingness-to-pay...

The National Science Foundation (NSF) Division of Information and Intelligent Systems awarded a $162,827 Project Grant to the University of Wisconsin - Madison, through the University of Wisconsin System, to develop an "Intelligent Pervasive Augmented Reality Therapy (IPAL)" system for managing opioid use disorder (OUD) and addiction. The 1-year project will integrate complementary psychotherapies like cognitive behavioral therapy and heart rate variability biofeedback with immersive...

Federal Grant Award Summary Brigham & Women's Hospital Inc. received a $557,105 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) for the Public Access Naloxone Design, Dissemination and Assessment (PANDDA) project, awarded April 1, 2026, with completion targeted for March 31, 2028. The project delivers a comprehensive, evidence-based framework for deploying public access naloxone (PAN) programs through two phases:...