Project Grant R41AI134187

Federal Project Grant Award Summary Fred Hutchinson Cancer Center received a $232,558 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 13, 2026, with completion targeted for March 31, 2028. The grant funds research and development of an innovative gene therapy approach utilizing adeno-associated virus (AAV)-delivered meganucleases to achieve durable control of genital...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Teardx, LLC will fund the development of a rapid, point-of-care diagnostic test to accurately detect ocular herpes simplex virus (HSV-1) infections. The project aims to create a user-friendly, minimally invasive sampling tool and assay that can be used by eye specialists and urgent care clinicians to quickly screen for active HSV-1 infections, which are a leading cause...

Grant Award Summary The University of Pittsburgh received a $250,682 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 19, 2026, with a completion date of January 31, 2028. This research initiative investigates the role of nuclear paraspeckles and speckles in regulating Herpes Simplex Virus-1 (HSV-1) infection in human neurons and the establishment of viral latency. The...

Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Connecticut Health Center a Project Grant totaling $263,375 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 20, 2026 through March 31, 2028. This award funds biomedical research investigating HSV (Herpes Simplex Virus) alkaline nuclease as a novel antiviral drug target. The research focuses on understanding the UL12 gene-encoded...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Massachusetts Medical School a $150,528 Project Grant on May 5, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support investigator-initiated biomedical research. The research will be conducted at UMMS's Worcester, Massachusetts location through June 30, 2029, and focuses on elucidating the mechanisms by which caspases restrict herpes simplex virus 1 (HSV-1) replication,...

Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $427,625 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 6, 2026, with completion targeted for January 31, 2028. The award funds development of a rapid point-of-care lateral flow strip assay (LFSA) device for detecting Herpes Simplex Virus (HSV) infections in both symptomatic and...

Federal Project Grant Award Summary Fred Hutchinson Cancer Center received a $270,591 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period of April 1, 2026 through March 31, 2028. The award supports development and clinical validation of a multiplex binding antibody assay for confirmatory Herpes Simplex Virus Types 1 and 2 (HSV-1/2) serological diagnosis. The proposed...

Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $524,626 to the University of Wisconsin-Madison on February 5, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research titled "A Chromatin Loop Controls the Expression of Anterograde Transport Genes During HSV-1 Latency." The project, which extends through January 31, 2031, investigates the mechanisms governing herpes...

Federal Grant Award Summary Zabbio, Inc. received a $248,531 Project Grant award dated August 8, 2025, from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a monoclonal antibody (MAB) therapy for neonatal herpes simplex virus (HSV) infections. The project, designated as a Fast Track Small Business Innovation Research (SBIR) initiative with a completion date of July 31, 2026, focuses on advancing...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $486,470 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 11, 2025 through July 31, 2027. The award funds the development and validation of direct-from-sample whole genome sequencing (WGS) methods for Neisseria gonorrhoeae (NG) that eliminate the need for isolate culturing. These methodological advances will be applied to generate...