Project Grant R36DA064916
- The National Institute on Drug Abuse awarded New York University $547,333 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a mixed-methods study identifying state-level implementation strategies for expanding access to extended take-home methadone doses in opioid treatment programs. The award funds a phased R61/R33 project examining how state agencies—including state opioid treatment authorities and Medicaid agencies—are facilitating adoption of...
- The National Institute on Drug Abuse awarded New York University $3.359 million on September 15, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a comprehensive evaluation of New York State's mobile methadone unit program. The project, titled "NY MOVES: Evaluating the Impact of New York's Methadone Outreach Vehicles," applies a mixed-methods and quasi-experimental design following the RE-AIM framework to assess program reach, effectiveness, adoption,...
- The National Institute on Drug Abuse awarded Yale University $641,138 on June 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a study examining methadone dose-associated risks and outcomes in opioid use disorder treatment, with particular focus on aging adults. The research leverages a national cohort of approximately 54,000 patients receiving care in the Department of Veterans Affairs, derived from the Veterans Aging Cohorts Study's national cohort...
- The National Institute on Drug Abuse awarded The Trustees of Columbia University in the City of New York $1,555,130 on May 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop quantitative evidence informing personalized, sequential medication-for-opioid-use-disorder (MOUD) treatment protocols. The research applies data fusion methodology to synthesize data from seven large MOUD trials conducted by the NIDA Clinical Trials Network, generating evidence-based...
- The National Institute on Drug Abuse awarded Loyola University of Chicago Health Sciences Campus $551,926 on May 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a large-scale longitudinal epidemiological study of polysubstance use and associated health outcomes. The recipient will leverage the Oracle EHR Real-World Data database, comprising 1.9 billion encounters from 113 million patients across 700 U.S. hospitals and clinics, to conduct four primary...
- The National Institute on Drug Abuse awarded the University of Pittsburgh $701,569 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct research on the use and effectiveness of medications for opioid use disorder in older adults with multimorbidity. The award funds quantitative studies of Medicare and Veterans Health Administration enrollees with diagnosed opioid use disorder and a qualitative study of older adults with opioid use disorder and...
- The National Institute on Drug Abuse awarded Icahn School of Medicine at Mount Sinai $100,228 on October 8, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to support research on opioid reward mechanisms. The award funds a project investigating the functional role of a novel cortical circuit connecting the dorsal peduncular nucleus to the ventral tegmental area in mediating opioid reward. The research employs barcoded anatomy resolved by sequencing combined with spatial...
- The National Institute on Drug Abuse awarded Icahn School of Medicine at Mount Sinai $796,299 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct single chromatin fiber multiomic mapping in opioid use disorder brain tissue. The recipient will perform genome-wide profiling of chromatin organization directly from frontal and cingulate cortex nuclei obtained from donors with chronic opioid use disorder. The work charts nucleosomal array organization,...
- The National Institute on Drug Abuse, part of the Department of Health and Human Services National Institutes of Health, awarded The Trustees of Columbia University in the City of New York $172,160 on December 9, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279). The award funds a postdoctoral fellowship to examine how HIV-specific state legal policies function as barriers to perinatal care and drug use treatment engagement among pregnant women. The research employs a...
- The National Institute on Drug Abuse awarded Yale University $336,250 on April 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a behavioral foundation model that transforms qualitative epidemiological survey responses into quantitative representations of substance use behaviors. The project harmonizes data from the National Epidemiologic Survey on Alcohol and Related Conditions III (NESARC-III), National Survey on Drug Use and Health (NSDUH), and UK Biobank...
The National Institute on Drug Abuse awarded New York University $103,607 on August 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct dissertation research on polysubstance use patterns and their associations with methadone maintenance treatment receipt and discontinuation among people who use drugs in New York State. The research uses a mixed-methods approach guided by the Social Ecological Model to identify latent polysubstance use patterns through urine toxicology and self-reported data, examining longitudinal and spatial associations with treatment outcomes. The work addresses gaps in understanding how concurrent use of opioids with benzodiazepines, cocaine, methamphetamine, fentanyl, xylazine, and other emerging substances influences treatment retention and non-fatal overdose risk, particularly among people who inject drugs. The project responds to the fourth wave of the overdose crisis, in which approximately two-thirds of opioid-related deaths now involve polysubstance use. Performance occurs in New York, New York, with a period of performance through July 31, 2028. This is a Project Grant, a form of assistance funding supporting basic, clinical, translational, and implementation research in substance use.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $103.6k | 8/5/26 |