Project Grant R35GM166536
- The National Institute of General Medical Sciences awarded the University of Wisconsin–Madison $124,929 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to fund research on how epithelial architecture regulates amoeboid migration strategies in vivo. The research examines cell migration through tissues, with focus on leukocyte movement within epithelial layers. Work uses intravital imaging in zebrafish to characterize how mechanical confinement drives...
- The National Institute of General Medical Sciences awarded the University of Wisconsin - Madison $413,001 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop computational systems for analyzing single-cell and spatial transcriptomics experiments. The recipient will create computational methods to improve downstream analysis of gene-expression data from single-cell and spatial transcriptomics experiments, which measure genome-wide expression in...
- The National Institute of General Medical Sciences awarded the University of Wisconsin - Madison $3.654 million on July 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support the National Center for Quantitative Biology of Complex Systems, which accelerates multi-omic quantitative biology research by providing researchers integrated access to mass spectrometry, lipidomics, and metabolomics technologies for comprehensive proteome, lipid, and metabolite...
- The National Institute of General Medical Sciences awarded the University of Wisconsin – Madison $580,507 on May 6, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate mechanisms governing midbody remnants in intercellular RNA communication. Over the five-year period of performance through February 28, 2031, the research will characterize the molecular cargo of midbody remnants—large extracellular vesicles released during cell division—across diverse...
- The National Institute of General Medical Sciences awarded The Medical College of Wisconsin, Inc. $390,000 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) for a project grant (R35GM161455) investigating metabolic regulation of immunity in C. elegans. The funded research elucidates how purine nucleotide metabolism regulates intestinal epithelial defense pathways, particularly focusing on intracellular pathogen response mechanisms in the nematode's...
- The National Institute of General Medical Sciences awarded $429,203 to the University of Wisconsin–Madison on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, Project Grant R35GM161252) to develop optically enhanced NMR methods for high-resolution analysis of biomolecular structure, dynamics, and interactions at sub-micromolar sensitivity under physiologically relevant conditions. The award supports integrated research combining NMR method...
- The National Institute of General Medical Sciences, a component of the Department of Health and Human Services National Institutes of Health, awarded $259,270 to the University of Wisconsin–Madison on August 20, 2026, under the Biomedical Research and Research Training program (CFDA 93.859). This Project Grant (R01GM170992) supports development of data infrastructure, analytic methods, and forecasting models to measure how federally funded biomedical research translates into improved health...
- The National Institutes of Health Office of the Director awarded $415,538 to the University of Wisconsin System, University of Wisconsin - Madison Division, on August 5, 2026, under the Trans-NIH Research Support program (CFDA 93.310), a Project Grant (R21AI200047). The award funds research on regulation of neutrophil heterogeneity and activation state using human induced pluripotent stem cell-derived neutrophils (iNeutrophils). The work employs single-cell multi-omics and imaging to...
- The National Institute of General Medical Sciences awarded the University of Wisconsin–Madison $116,005 on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support molecular research on neutrophil reverse migration in wound healing. The award funds the K99 phase of a study examining neutrophil subpopulations and their role in inflammation resolution. The research identifies key neutrophil subpopulations involved in reverse migration, tracks their...
- The National Institute of General Medical Sciences awarded the University of Wisconsin System $418,331 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) for advanced statistical methods for microbiome data analysis. The award funds development of innovative batch-effect correction methods, meta-analysis techniques, and robust causal-inference tools to address methodological gaps in microbiome research. The recipient will develop and disseminate...
The National Institute of General Medical Sciences awarded the University of Wisconsin – Madison $412,201 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate how metabolic microenvironments direct immune cell plasticity and function. The research project develops and applies an organotypic array for culture in live-cell environments (ORACLE), a micropatterned 3D hydrogel platform with functional vasculature that enables spatial and temporal manipulation and monitoring of the metabolic niche. The recipient will use this system to study how perturbations in metabolite availability affect immune cell differentiation and adaptation, with preliminary focus on natural killer cell phenotypes including memory NK cells. The work addresses technological gaps in understanding how cells respond to changes in metabolite composition as they migrate from the vasculature into specific organs, and how these adaptations occur over time. Work is performed in Madison, Wisconsin. The period of performance extends from September 1, 2026, through April 30, 2031. This is a project grant, the standard NIH assistance type for investigator-initiated research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $412.2k | 8/17/26 |