Project Grant R35GM166021
Award Date 8/10/26
Completion Date 4/30/31
Dollars Obligated $475K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92037, USA
Similar Awards
- Federal Project Grant Award Summary The Salk Institute for Biological Studies received a $1.2 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) awarded July 15, 2025, with a completion date of July 14, 2026. The award funds the acquisition and deployment of a Thermo Fisher Scientific Orbitrap IQ-X Tribrid mass spectrometer equipped with an Ultrahigh Performance Liquid Chromatography...
- The National Institute of General Medical Sciences awarded The Salk Institute for Biological Studies $515,625 on June 12, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate fundamental mechanisms of cytoskeletal dynamics and transport, with focus on how connector proteins link molecular motors to cellular cargo and facilitate transport along microtubule tracks. The research examines two primary areas: the role of spectraplakin proteins, which link...
- The National Institute of General Medical Sciences awarded The Salk Institute for Biological Studies $625,589 on July 10, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the molecular determinants that regulate cohesin-mediated loop extrusion and stability in vivo. The research examines how the cohesin complex and CTCF protein organize chromatin through loop extrusion—a process that has been observed in vitro and in preliminary cellular studies...
- The National Institutes of Health Office of the Director awarded The Salk Institute for Biological Studies $187,500 on August 1, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to develop computational models of retinal rod photoreceptor synapses and advance the MCell4/CellBlender simulation software suite. The recipient will create anatomically detailed Monte Carlo simulations integrating empirical findings on glutamate dynamics at rod synapses, addressing how postsynaptic...
- The National Institute of General Medical Sciences, part of the Department of Health and Human Services National Institutes of Health, awarded The Leland Stanford Junior University $1,733,072 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop a multi-resolution open-top light-sheet expansion microscopy system. The project will advance 3D microscopy for high-throughput imaging of expanded tissues with ultra-high resolution—sub-150 nanometer...
- The National Institute of General Medical Sciences awarded Third Floor Materials, Inc. (3FM) $298,111 on September 2, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop a high-throughput snapshot hyperspectral imager for multiplexed fluorescence microscopy. The system combines proprietary plasmonic filter arrays with backside-illuminated CMOS sensors to enable capture of complete hyperspectral datacubes—containing both spectral and spatial...
- The National Institute of General Medical Sciences awarded $430,109 to The Regents of the University of California, operating Lawrence Berkeley National Laboratory, on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop deeply subwavelength near infrared imaging technology using avalanching nanoparticles. The project addresses fundamental limitations of live-cell optical microscopy by creating avalanching nanoparticles (ANPs) that upconvert incident...
- The National Institute of General Medical Sciences awarded the University of California, San Diego $369,347 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct high-resolution structural analysis of megasynthases by cryo-electron microscopy. The project develops molecular tools and probes to enable structural visualization of protein-protein interactions within carrier protein-dependent biosynthetic pathways, including fatty acid synthase,...
- The National Institute of General Medical Sciences awarded the University of California, San Diego $125,000 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop photocatalytic proximity labeling platforms and near-infrared photocaging methods that map protein interactions in lipid-based systems and hydrophobic tag protein degraders. The project, titled "Harnessing Hydrophobic Interactions for Photocaging and Photoproximity Labeling,"...
- The National Institute of General Medical Sciences awarded the California Institute of Technology $1,979,208 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and advance hybridization chain reaction methods for multiplex, quantitative, high-resolution imaging of RNA, protein, and molecular complexes in biological specimens. The research addresses longstanding limitations in in situ hybridization and immunohistochemistry methods by...