Project Grant R35GM165848
- Federal Project Grant Award Summary The Salk Institute for Biological Studies received a $1.2 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) awarded July 15, 2025, with a completion date of July 14, 2026. The award funds the acquisition and deployment of a Thermo Fisher Scientific Orbitrap IQ-X Tribrid mass spectrometer equipped with an Ultrahigh Performance Liquid Chromatography...
- Federal Project Grant Award Summary The Salk Institute for Biological Studies received a $943,750 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 5, 2025, with completion targeted for July 31, 2030. The research project investigates peptide-receptor signaling in plant-microbe interactions, specifically examining how plant cells make cellular decisions when exposed to...
- Federal Project Grant Award Summary The Salk Institute for Biological Studies received a $515,625 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded May 13, 2026, with a completion date of February 28, 2031. The award funds fundamental research into the establishment and modulation of DNA (deoxyribonucleic acid) methylation patterns during plant development, utilizing Arabidopsis...
- Federal Grant Award Summary The Salk Institute for Biological Studies received a $122,763 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) for the period February 1, 2026 through January 31, 2028. The award supports fundamental basic research investigating the role of chromatin structure in nuclear receptor function, specifically examining how retinoic acid receptor-related orphan receptor G...
- Federal Grant Award Summary The Salk Institute for Biological Studies received a $220,000 Project Grant from the National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded June 1, 2025, with a completion date of May 31, 2028. This collaborative research initiative will develop advanced microcoaxial electro-optical mechanically flexible probes for minimally invasive interfacing with spinal neural circuits. The project will produce dual-modality probes with a footprint smaller...
- Federal Project Grant Award Summary The Salk Institute for Biological Studies received a $355,185 project grant awarded on August 7, 2025, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant supports research investigating astrocyte-neuron interactions in Rett Syndrome and Fragile X Syndrome, with a completion date of February 28, 2027. The research...
- Federal Grant Award Summary The University of California, San Diego received a $370,550 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective May 1, 2026 through February 28, 2031. This award funds the development of the Intracellular Protein Organization Landscape (IPOL), a quantitative computational framework designed to characterize and define cell types and states based on spatial...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the Salk Institute for Biological Studies a Project Grant totaling $150,104 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective February 1, 2026, with a completion date of October 31, 2028. This award funds research to develop reproducible methods for growing brain organoids with enhanced structural complexity, cellular...
- Federal Project Grant Award Summary The University of California, San Diego received a $479,738 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective May 1, 2026 through April 30, 2031. This award supports fundamental research investigating the functions of kinetochore machinery—specialized protein structures that facilitate accurate chromosome segregation during cell division. The...
- Summary of Federal Grant Award The University of California, San Diego received a $369,347 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2026 through June 30, 2031. This award supports high-resolution structural analysis of megasynthases using cryo-electron microscopy (cryo-EM). The research focuses on developing and applying molecular tools and probes to capture...
The Salk Institute for Biological Studies received a $515,625 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded June 12, 2026, with completion targeted for March 31, 2031. This fundamental basic science research project investigates cytoskeletal connector proteins and their roles in cellular transport mechanisms. The research focuses on two primary objectives: (1) elucidating the structural and biochemical functions of spectraplakin proteins, which link actin and microtubule cytoskeletal components and possess previously uncharacterized adenosine triphosphatase (ATPase) domains, and (2) characterizing dynamic interactions between molecular motors—specifically cytoplasmic dynein-1—and adapter proteins that regulate cargo transport along microtubule tracks. The deliverables from this research initiative include structural characterization data, biochemical analyses, cell biology findings, and mechanistic insights into connector protein functions and motor-cargo interactions. These research outputs are intended to advance understanding of fundamental cellular processes and establish foundational knowledge relevant to disease mechanisms, as disruptions in connector proteins are implicated in neurodevelopmental disorders, neurodegenerative diseases, and cancers. The project will be conducted at the Salk Institute's La Jolla, California facility.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $515.6k | 6/11/26 |