Project Grant R35GM165568
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University received a $410,605 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026, through March 31, 2031. The award supports research and development of accurate and computationally efficient solvent models for molecular simulations in structural biology and drug design applications. The...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $414,482 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 24, 2025, with a completion date of June 30, 2027. The research focuses on developing an improved oncolytic virus therapeutic to treat glioblastoma, an aggressive brain cancer with poor prognosis. The project aims to...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $422,314 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026, through January 31, 2031. The award funds fundamental research on specialized adaptations in the model alpha-proteobacterium Sinorhizobium meliloti, with particular focus on the bacterium's...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $421,560 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 12, 2026, with completion targeted for May 31, 2028. The project, titled "Characterizing an Alternative Genetic Pathway Critical for the Virulence of Brucella," focuses on identifying and...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $422,355 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 23, 2025, with completion targeted for June 30, 2027. The grant funds mechanistic and structural studies examining the signaling histidine kinase GacS from Pseudomonas aeruginosa, a nosocomial...
- Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $400,000 Project Grant award from the National Science Foundation (NSF) Division of Environmental Biology under the Biological Sciences program (CFDA 47.074), effective January 15, 2027, with completion targeted for December 31, 2028. The award funds research examining eco-evolutionary drivers of viral spillover from wildlife to humans, with specific focus on orthohantaviruses and their...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $452,769 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 11, 2025, to conduct research on the impact of BDGR-49 treatment on Venezuelan Equine Encephalitis Virus (VEEV) induced neurological sequelae. The research addresses a critical public health gap by...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $112,256 Project Grant awarded April 22, 2026, by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research investigating the epigenetic basis of monocyte exhaustion memory following sepsis, with completion scheduled for March 31, 2027. The research addresses a critical...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $392,338 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective May 15, 2026, with completion targeted for April 30, 2031. The award supports fundamental neuroscience research investigating synaptic signaling mechanisms in brains...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $300,000 Project Grant award dated September 15, 2025, from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074). The research deliverables will focus on elucidating nickel delivery pathways and metallochaperone proteins in methanogenic archaea—microorganisms that produce methane through unique...
Virginia Polytechnic Institute & State University (Virginia Tech) received a $402,500 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award, effective July 1, 2026, and concluding February 28, 2031, funds investigator-initiated research examining mechanisms of virus-host conflict at the cellular level, specifically how viral and host factors determine cell fate decisions between survival and regulated cell death (RCD). The research will establish frameworks to understand how spatial context, intracellular and extracellular danger signals, and viral genotypes drive different RCD modes across cell types and viruses, including multicellular three-dimensional (3D) tissue-relevant systems. The project delivers fundamental scientific research outputs linking viral genotype to host cell transcriptomic phenotypes at the single-cell level, with the ultimate goal of creating predictive frameworks for how viral genotypes perturb cell-level phenotypes across experimental contexts. This basic research advances understanding of biological processes underlying virus-host interactions and lays groundwork for potential advances in viral disease diagnosis and treatment. Work will be conducted at Virginia Tech's Blacksburg, Virginia campus, a research-intensive land-grant institution with established capacity in NIH-funded biomedical research across multiple scientific domains.Summary of Federal Project Grant Award
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $402.5k | 6/23/26 |