Project Grant 2531607
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $1,087,895.00 to the University of Nebraska to identify and characterize spatially coupled biochemical processes in methanogenic archaea. The research aims to investigate how the enzymes used by these microbes work together to efficiently convert low-energy substrates like acetate and methanol into the high-energy fuel methane gas. By revealing the enzyme interactions within...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Virginia Polytechnic Institute & State University a $805,420 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for the period of August 1, 2021 through July 31, 2025. The grant funds collaborative research on chemotactic signaling in Sinorhizobium meliloti symbiotic plant host interaction. The Biological Sciences program aims to promote advancement in the biological sciences...
- This three-year project grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $462,000 to Virginia Polytechnic Institute and State University from July 2021 through June 2024. The grant supports mechanistic investigation of radical SAM methylases involved in tetrahydromethanopterin biosynthesis. A sub-award of $100,000 is also provided to Auburn University to support related research into the mechanistic...
- Virginia Polytechnic Institute & State University (Virginia TECH) was awarded a $523,102 Project Grant from the National Science Foundation Division of Environmental Biology on March 1, 2022 to fund research under the Biological Sciences program (CFDA 47.074) through February 28, 2025. The grant will support research investigating the relationship between limits to evolvability and the maximal sustainable niche of generalist species. Specifically, the funding will enable scientists at...
- The National Science Foundation (NSF) awarded a $800,000 Project Grant under the Biological Sciences program (CFDA 47.074) to The Washington University's Office of Sponsored Research Services Division. The 3-year project aims to investigate the metabolic cooperation between a phototrophic bacterium and a methanogenic archaeon, and how this "syntrophic" interaction influences methane production and the nitrogen cycle in anoxic environments. The research will shed light on how these...
- Virginia Polytechnic Institute & State University (Virginia Tech) was awarded a $493,499 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems. The award will support research from December 2021 through November 2024 under the NSF Engineering (ENG) program (CFDA #47.041). Specifically, Virginia Tech will conduct experimental and computational modeling of bacteria transport and adhesion in the microvasculature....
- The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded a $457,300 Project Grant to Virginia Polytechnic Institute & State University (Virginia Tech) to identify mRNA dynamics and cis-regulatory elements that support low-noise gene expression in cells. The key objectives of this 3-year grant are to: 1) develop an adequate expression model for genes exhibiting ultra-low noise levels, and 2) survey hundreds of mammalian genes to determine the prevalence of genes...
- The National Science Foundation (NSF) Biological Sciences Federal Grant Program (CFDA 47.074) awarded a $819,654 Project Grant to the University of North Texas on February 1, 2025. The grant supports research to advance the understanding of methanotrophic bacteria metabolism and physiology. The project aims to leverage recent genetic tools and CRISPR interference techniques to further define the role of CO2 and the Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) in the metabolism and...
- The Virginia Polytechnic Institute and State University (Virginia Tech) received a two-year, $200,000 Project Grant from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems to develop nanoplasmonic mesh-based biosensors for in situ spatiotemporal monitoring of biofilm activities. The goal is to incorporate uniform nanoplasmonic hotspot arrays within microbial biofilms to enable real-time, spatially-resolved surface-enhanced Raman...
- The National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $752,886 Project Grant to Virginia Polytechnic Institute & State University (Virginia Tech) on August 1, 2025. The grant, titled "THE PLASTISPHERE OF POND ECOSYSTEMS: UNDERSTANDING THE FUNCTION AND FATE OF NOVEL CARBON IN BIOGEOCHEMICAL HOTSPOTS", will fund research to investigate the impact of plastic debris on pond ecosystems. The project aims to study how plastics, as a form...
The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program has awarded Virginia Polytechnic Institute & State University (Virginia Tech) a $300,000 Project Grant to elucidate the proteins involved in trafficking and delivering nickel to nickel-dependent enzymes in methanogenic archaea. The project aims to define the nickel homeostasis mechanisms, including nickel uptake, storage/export, and enzyme assembly, in these microorganisms that produce methane as a byproduct of their unique energy metabolism. The award period is from September 15, 2025, to August 31, 2028. The knowledge gained from this project could support efforts to engineer methanogenic metabolism to produce biofuels and commodity chemicals from low-cost precursors. Additionally, the project will provide training and professional development opportunities for undergraduate and graduate students, as well as engage middle and high school students in hands-on microbiology activities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $300.0k | 7/29/25 |