Project Grant R35GM164100
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stony Brook University $432,569 on March 5, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support a five-year research initiative through February 28, 2031. The project, titled "Deciphering the Regulatory Mechanisms of Extracellular Particle-Mediated Signaling," investigates the fundamental mechanisms by which cells release and utilize...
- Federal Project Grant Award Summary The Research Foundation for the State University of New York, doing business as Stony Brook University, received a $481,722 Project Grant awarded September 1, 2025, through the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074). The three-year research initiative, scheduled for completion by August 31, 2028, focuses on investigating the synthesis and enzymatic mechanisms of...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stony Brook University a Project Grant of $429,262 under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research on germline ribosomal DNA (rDNA) maintenance mechanisms. The award, effective May 1, 2026 through December 31, 2030, funds a five-year research initiative investigating how cells restore lost ribosomal DNA copies across generations to maintain...
- Federal Grant Award Summary Stony Brook University received a $1.81M project grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded July 1, 2025, with a completion date of June 30, 2030. The grant supports the continuation of the Medical Scientist Training Program (MSTP), an MD-PhD program that has operated continuously since 1992. The program delivers integrated physician-scientist training that...
- Federal Project Grant Award Summary Stony Brook University received a $249,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through August 31, 2028. This award supports fundamental biomedical research investigating the dynamic mechanisms of transcriptional coactivator function in Notch signaling, a critical developmental pathway implicated in multiple tissue...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Research Foundation for the State University of New York a Project Grant totaling $434,169 under the Biomedical Research and Research Training program (CFDA 93.859) for the period of March 1, 2026, through February 28, 2031. This research project, conducted at the University at Buffalo in Buffalo, New York, focuses on characterizing polysaccharide utilization pathways and antimicrobial resistance...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Stony Brook University a $3.13 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 23, 2025, with completion targeted for June 30, 2029. The grant funds research to develop new therapeutic strategies targeting STS-1 and STS-2 phosphatases as a means to enhance antimicrobial immune responses. The project deliverables include the identification...
- Federal Grant Award Summary Stony Brook University received a $436,001 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025 through July 31, 2027. The award supports development of an efficient and accessible spatial transcriptomics platform designed to deliver gene expression data at single-cell resolution within tissue spatial context. The project addresses current...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $436,361.00 under the Biomedical Research and Research Training program (CFDA 93.859) to support a five-year project (August 1, 2025 – July 31, 2030) focused on advancing protein structure determination methodologies. The Research Foundation for the State University of New York, serving as the fiscal agent for research conducted in Buffalo, will develop innovative computational algorithms and...
- Federal Grant Award Summary The Mount Desert Island Biological Laboratory received a $464,750 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded March 15, 2026, with completion targeted for January 31, 2031. This award supports fundamental research exploring tissue-specific mechanisms and requirements for nucleolin organization in living organisms. The research utilizes Caenorhabditis...
Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded Stony Brook University $432,892 in Project Grant funding effective June 1, 2026, through May 31, 2031. This five-year research initiative, conducted at Stony Brook's facilities in Stony Brook, New York, delivers fundamental basic research aimed at elucidating the structural organization and adaptive mechanisms of the mycobacterial cell envelope. The research program addresses three primary research questions examining how mycobacteria adapt surface proteins, transport and modulate lipoproteins, and reorganize membranes in response to environmental stress. Understanding these cell envelope dynamics is designed to establish foundational knowledge that could inform more effective antimicrobial targeting strategies, particularly for pathogenic non-tuberculous mycobacteria (NTM) that cause antibiotic-refractory lung infections. The research utilizes an integrated approach combining chemical biology, biophysics, and microbiology methodologies, supported by a network of institutional collaborations. By investigating the unique properties of the mycomembrane—an extremely hydrophobic outer membrane-like barrier that contributes to mycobacterial antibiotic resistance—this project delivers investigator-initiated basic research that advances understanding of bacterial adaptation and survival mechanisms relevant to infectious disease treatment and prevention. The award represents NIGMS's commitment to funding meritorious biomedical research that establishes scientific foundations for future diagnostic, therapeutic, and preventive advances.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $432.9k | 5/5/26 |